| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | JAK1;JAK1A;JAK1B;Tyrosine-protein kinase JAK1;Janus kinase 1;JAK-1 |
| Gene ID | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human JAK1 around the phosphorylation site of Tyr1022. AA range:988-1037 |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Concentration | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® JAK1 (Phospho Tyr1022) Rabbit Polyclonal Antibody is a rabbit polyclonal antibody from UcallM Biosciences Inc, raised against JAK1. Recognizes Phospho. It has been validated for Immunofluorescence, Western Blot, Immunoprecipitation, Immunohistochemistry, ELISA and reacts with Human, Mouse, Rat.
Validated Applications
| Target | JAK1 |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat |
| Applications | Immunofluorescence, Western Blot, Immunoprecipitation, Immunohistochemistry, ELISA |
| Purification | Affinity Purified |
| Specificity | Phospho-JAK1 (Y1022) Polyclonal Antibody detects endogenous levels of JAK1 protein only when phosphorylated at Y1022. |
| Molecular Weight | Observed: 132 kDa |
| UniProt / Swiss-Prot | P23458 (Human) | P52332 (Mouse) |
Recommended dilutions: IF 1:50-200;WB 1:200-1:1000;IHC 1:100-1:300;ELISA 1:10000;Not yet tested in other applications
Immunogen / Antigen
The antiserum was produced against synthesized peptide derived from human JAK1 around the phosphorylation site of Tyr1022. AA range:988-1037
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat. Confirm suitability for untested species before use.
Scientific Background
This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Safety & Handling
This antibody is validated for Immunofluorescence, Western Blot, Immunoprecipitation, Immunohistochemistry, ELISA. Recommended dilutions: IF 1:50-200;WB 1:200-1:1000;IHC 1:100-1:300;ELISA 1:10000;Not yet tested in other applications
Confirmed reactivity: Human, Mouse, Rat. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
