| Field | Specification |
|---|---|
| Target | |
| Alternative names | DXS1272E;Histone demethylase JARID1C;JARID1C;JmjC domain containing protein SMCX;Jumonji AT rich interactive domain 1C;Jumonji, AT rich interactive domain 1C;RBP2 like;Jumonji/ARID domain-containing protein 1C;KDM5C;KDM5C_HUMAN;Lysine;K;specific demethylase 5C;Lysine-specific demethylase 5C;MRXJ;MRXSCJ;MRXSJ;Protein SmcX;Protein Xe169;rbp2 like protein;Selected cDNA on X;SMCX;Smcx homolog X chromosome;SmcX protein;SmcX protein;Smcy homolog X linked;XE169;Xe169 protein;Xe169 protein. |
| Gene ID | |
| Host | |
| Clonality | |
| Reactivity | |
| Applications | |
| Immunogen | Purified recombinant human KDM5C / Jarid1C / SMCX protein fragments expressed in E.coli |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® KDM5C/Jarid1C/SMCX Mouse Monoclonal Antibody is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against KDM5C/Jarid1C/SMCX. It has been validated for Western Blot, Immunofluorescence and reacts with Human.
Validated Applications
| Target | KDM5C/Jarid1C/SMCX |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Conjugate | Unconjugated |
| Reactivity | Human |
| Applications | Western Blot, Immunofluorescence |
| Purification | Affinity Purified |
| Specificity | This antibody detects endogenous levels of KDM5C / Jarid1C / SMCX and does not corss-react with related proteins |
| Molecular Weight | Observed: 220 kDa |
| UniProt / Swiss-Prot | P41229 (Human) | P41230 (Mouse) |
Recommended dilutions: WB 1:1000;ICC 1:150
Immunogen / Antigen
Purified recombinant human KDM5C / Jarid1C / SMCX protein fragments expressed in E.coli
Reactivity Notes
Confirmed cross-reactivity: Human. Confirm suitability for untested species before use.
Scientific Background
This gene is a member of the SMCY homolog family and encodes a protein with one ARID domain, one JmjC domain, one JmjN domain and two PHD-type zinc fingers. The DNA-binding motifs suggest this protein is involved in the regulation of transcription and chromatin remodeling. Mutations in this gene have been associated with X-linked mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
Safety & Handling
This antibody is validated for Western Blot, Immunofluorescence. Recommended dilutions: WB 1:1000;ICC 1:150
Confirmed reactivity: Human. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
