| Field | Specification |
|---|---|
| Target | |
| Alternative names | 58 kDa cytokeratin;CK 5;CK-5;CK5;Cytokeratin-5;Cytokeratin5;DDD;DDD1;EBS 2;EBS2;epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types;K2C5_HUMAN;K5;Keratin 5;epidermolysis bullosa simplex Dowling-Meara/Kobner/Weber-Cockayne types;keratin 5;epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types;Keratin 5;Keratin;keratin complex 2, basic, gene 5;Keratin Type II Cytoskeletal 5;keratin, type II cytoskeletal 5;Keratin-5;Keratin5;KRT 5;KRT 5A;KRT5;KRT5A;type II cytoskeletal 5;Type-II keratin Kb5. |
| Gene ID | |
| Host | |
| Clonality | |
| Reactivity | |
| Applications | |
| Immunogen | Purified recombinant human KRT5 beta protein fragments expressed in E.coli. |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® Keratin(50-60kDa) Mouse Monoclonal Antibody is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against Keratin(50-60kDa). It has been validated for Western Blot and reacts with Human, Mouse, Rat.
Validated Applications
| Target | Keratin(50-60kDa) |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat |
| Applications | Western Blot |
| Purification | Affinity Purified |
| Specificity | This antibody detects endogenous levels of Keratin(50-60kDa) proteins. |
| Molecular Weight | Observed: 62 kDa |
| UniProt / Swiss-Prot | P13647 (Human) | Q922U2 (Mouse) |
Recommended dilutions: WB 1:2000
Immunogen / Antigen
Purified recombinant human KRT5 beta protein fragments expressed in E.coli.
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat. Confirm suitability for untested species before use.
Scientific Background
keratin 5(KRT5) Homo sapiens The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008]
Safety & Handling
This antibody is validated for Western Blot. Recommended dilutions: WB 1:2000
Confirmed reactivity: Human, Mouse, Rat. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
