| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | Kinesin-like protein KIF7 |
| Gene ID | |
| Host | |
| Clone | |
| Clonality | |
| Reactivity | |
| Applications | |
| Immunogen | Synthetic Peptide of Kif 7 |
| Conjugate | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® Kif 7 Mouse Monoclonal Antibody (3F8) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against Kif 7. It has been validated for Immunohistochemistry, Immunofluorescence and reacts with Human, Mouse, Rat.
Validated Applications
| Target | Kif 7 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 3F8 |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat |
| Applications | Immunohistochemistry, Immunofluorescence |
| Purification | Affinity Purified |
| Specificity | The antibody detects endogenous Kif 7 proteins. |
| UniProt / Swiss-Prot | Q2M1P5 (Human) | B7ZNG0 (Mouse) |
Recommended dilutions: IHC 1:50-200;IF 1:50-200
Immunogen / Antigen
Synthetic Peptide of Kif 7
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat. Confirm suitability for untested species before use.
Scientific Background
This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies. [provided by RefSeq, Oct 2011]
Safety & Handling
This antibody is validated for Immunohistochemistry, Immunofluorescence. Recommended dilutions: IHC 1:50-200;IF 1:50-200
Confirmed reactivity: Human, Mouse, Rat. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone 3F8.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.