U-Blot® Kv10.1 Rabbit Polyclonal Antibody

SKU:BHA21817115
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UcallM Biosciences Inc
UcallM Biosciences Inc
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Overview
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Anti-Kv10.1 antibody (Rabbit host, polyclonal, Unconjugated). Validated for Immunohistochemistry, Immunofluorescence with reactivity to Human, Rat, Mouse.
Clonality Polyclonal
Host Rabbit
Reactivity Human, Rat, Mouse
Conjugate Unconjugated
Isotype IgG
Applications Immunohistochemistry, Immunofluorescence
Options selector
Catalog no. Size
WP5837-50 50 uL
WP5837-100 100 uL
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 50 uL
  • Lead time: options listed in "Availability Content"; other statuses may take longer.
  • Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
  • Shipping: cold-chain shipment (typically with ice packs).
  • Upon receipt: store at recommended temperature as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Target Kv10.1
Antigen
  • Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv10.1) (Voltage-gated potassium channel subunit Kv6.3)
Alternative names KCNG3;Potassium voltage-gated channel subfamily G member 3;Voltage-gated potassium channel subunit Kv10.1;Voltage-gated potassium channel subunit Kv6.3
Gene ID 170850 (Human)
Host Rabbit
Clonality
  • Polyclonal
Isotype
  • IgG
Reactivity
  • Human
  • Rat
  • Mouse
Applications
  • Immunohistochemistry
  • Immunofluorescence
Immunogen Synthetic Peptide of Kv10.1 AA range: 335-385
Conjugate
  • Unconjugated
Molecular weight Observed: 50 kDa
Purification Affinity Purified
Cellular localization Cell membrane ; Multi-pass membrane protein . Cytoplasm . Has to be associated with KCNB1 or possibly another partner to get inserted in the plasma membrane (PubMed:12060745). Colocalizes with KCNB1 at the plasma membrane (PubMed:12060745, PubMed:19074135). Remains intracellular in the absence of KCNB1 (PubMed:12060745). .
Concentration 1 mg/ml
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage -15°C to -25°C/1 year(Do not lower than -25°C)
Catalog no. (Mfr.) WP5837
Main SKU BHA21817115
Antibody

Product Overview

U-Blot® Kv10.1 Rabbit Polyclonal Antibody is a rabbit polyclonal antibody from UcallM Biosciences Inc, raised against Kv10.1. It has been validated for Immunohistochemistry, Immunofluorescence and reacts with Human, Rat, Mouse.

Validated Applications

Target Kv10.1
Host Rabbit
Clonality Polyclonal
Isotype IgG
Conjugate Unconjugated
Reactivity Human, Rat, Mouse
Applications Immunohistochemistry, Immunofluorescence
Purification Affinity Purified
Specificity Kv10.1 protein(A259) detects endogenous levels of Kv10.1
Molecular Weight Observed: 50 kDa
UniProt / Swiss-Prot Q8TAE7 (Human) | P59053 (Mouse) | Q8R523 (Rat)

Recommended dilutions: IHC 1:100-200;IF 1:50-200

Immunogen / Antigen

Synthetic Peptide of Kv10.1 AA range: 335-385

Reactivity Notes

Confirmed cross-reactivity: Human, Rat, Mouse. Confirm suitability for untested species before use.

Scientific Background

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This member is a gamma subunit functioning as a modulatory molecule. Alternative splicing results in two transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

Safety & Handling

For Research Use Only (RUO). Not for diagnostic or therapeutic use. Store as indicated: -15°C to -25°C/1 year(Do not lower than -25°C)
What applications is this antibody validated for?

This antibody is validated for Immunohistochemistry, Immunofluorescence. Recommended dilutions: IHC 1:100-200;IF 1:50-200

What species does it react with?

Confirmed reactivity: Human, Rat, Mouse. Other species should be validated by the user.

Is this antibody conjugated?

Conjugate: Unconjugated.

How should it be stored?

Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)

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