| Field | Specification |
|---|---|
| Target | |
| Alternative names | FLJ94114;LEP;LEP_HUMAN;LEPD;Leptin;murine obesity homolog;Leptin;obesity homolog, mouse;Leptin;Leptin Murine Obesity Homolog;Leptin Precursor Obesity Factor;OB;Obese Protein;Obese, mouse, homolog of;Obesity;Obesity factor;Obesity factor;Obesity homolog mouse;Obesity Murine Homolog Leptin;OBS;OTTHUMP00000212285. |
| Gene ID | |
| Host | |
| Clonality | |
| Reactivity | |
| Applications | |
| Immunogen | Purified recombinant full length of human Leptin protein expressed in E.coli. |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® Leptin Mouse Monoclonal Antibody is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against Leptin. It has been validated for ELISA and reacts with Human.
Validated Applications
| Target | Leptin |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Conjugate | Unconjugated |
| Reactivity | Human |
| Applications | ELISA |
| Purification | Affinity Purified |
| Specificity | This antibody detects human Leptin proteins. |
| Molecular Weight | Observed: 16 kDa |
| UniProt / Swiss-Prot | P41159 (Human) | P41160 (Mouse) |
Recommended dilutions: ELISA 1:10000-20000
Immunogen / Antigen
Purified recombinant full length of human Leptin protein expressed in E.coli.
Reactivity Notes
Confirmed cross-reactivity: Human. Confirm suitability for untested species before use.
Scientific Background
This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development. [provided by RefSeq, Jul 2008]
Safety & Handling
This antibody is validated for ELISA. Recommended dilutions: ELISA 1:10000-20000
Confirmed reactivity: Human. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
