U-Blot® LPL Mouse Monoclonal Antibody

SKU:BHA21801881
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Suppliers
UcallM Biosciences Inc
UcallM Biosciences Inc
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Overview
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Anti-LPL antibody (Mouse host, monoclonal, Unconjugated). Validated for Western Blot, ELISA with reactivity to Human.
Clonality Monoclonal
Host Mouse
Reactivity Human
Conjugate Unconjugated
Applications Western Blot, ELISA
Options selector
Catalog no. Size
WM0302-50 50 uL
WM0302-100 100 uL
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 50 uL
  • Lead time: options listed in "Availability Content"; other statuses may take longer.
  • Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
  • Shipping: cold-chain shipment (typically with ice packs).
  • Upon receipt: store at recommended temperature as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Target LPL
Antigen
  • Lipoprotein lipase
Alternative names LPL;LIPD;Lipoprotein lipase;LPL
Gene ID 4023 (Human)
Host Mouse
Clonality
  • Monoclonal
Reactivity
  • Human
Applications
  • Western Blot
  • ELISA
Immunogen Purified recombinant fragment of LPL expressed in E. Coli.
Conjugate
  • Unconjugated
Molecular weight Calculated: 53 kDa
Purification Affinity Purified
Cellular localization Cell membrane ; Peripheral membrane protein ; Extracellular side . Secreted . Secreted, extracellular space, extracellular matrix . Newly synthesized LPL binds to cell surface heparan proteoglycans and is then released by heparanase. Subsequently, it becomes attached to heparan proteoglycan on endothelial cells (PubMed:27811232). Locates to the plasma membrane of microvilli of hepatocytes with triglyceride-rich lipoproteins (TRL). Some of the bound LPL is then internalized and located inside non-coated endocytic vesicles (By similarity). .
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage -15°C to -25°C/1 year(Do not lower than -25°C)
Catalog no. (Mfr.) WM0302
Main SKU BHA21801881
Antibody

Product Overview

U-Blot® LPL Mouse Monoclonal Antibody is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against LPL. It has been validated for Western Blot, ELISA and reacts with Human.

Validated Applications

Target LPL
Host Mouse
Clonality Monoclonal
Conjugate Unconjugated
Reactivity Human
Applications Western Blot, ELISA
Purification Affinity Purified
Specificity LPL Monoclonal Antibody detects endogenous levels of LPL protein.
Molecular Weight Calculated: 53 kDa
UniProt / Swiss-Prot P06858 (Human) | P11152 (Mouse)

Recommended dilutions: WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.

Immunogen / Antigen

Purified recombinant fragment of LPL expressed in E. Coli.

Reactivity Notes

Confirmed cross-reactivity: Human. Confirm suitability for untested species before use.

Scientific Background

lipoprotein lipase(LPL) Homo sapiens LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism. [provided by RefSeq, Jul 2008]

Safety & Handling

For Research Use Only (RUO). Not for diagnostic or therapeutic use. Store as indicated: -15°C to -25°C/1 year(Do not lower than -25°C)
What applications is this antibody validated for?

This antibody is validated for Western Blot, ELISA. Recommended dilutions: WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.

What species does it react with?

Confirmed reactivity: Human. Other species should be validated by the user.

Is this antibody conjugated?

Conjugate: Unconjugated.

How should it be stored?

Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)

Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.

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