U-Blot® LRRK2 Rabbit Polyclonal Antibody

SKU:BHA21813558
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UcallM Biosciences Inc
UcallM Biosciences Inc
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Overview
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Anti-LRRK2 antibody (Rabbit host, polyclonal, Unconjugated). Validated for Immunohistochemistry, Immunofluorescence with reactivity to Human, Mouse.
Clonality Polyclonal
Host Rabbit
Reactivity Human, Mouse
Conjugate Unconjugated
Isotype IgG
Applications Immunohistochemistry, Immunofluorescence
Options selector
Catalog no. Size
WP2279-50 50 uL
WP2279-100 100 uL
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 50 uL
  • Lead time: options listed in "Availability Content"; other statuses may take longer.
  • Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
  • Shipping: cold-chain shipment (typically with ice packs).
  • Upon receipt: store at recommended temperature as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Target LRRK2
Antigen
  • Leucine-rich repeat serine/threonine-protein kinase 2 (Dardarin)
Gene ID 120892 (Human)
Host Rabbit
Clonality
  • Polyclonal
Isotype
  • IgG
Reactivity
  • Human
  • Mouse
Applications
  • Immunohistochemistry
  • Immunofluorescence
Immunogen Synthesized peptide derived from part region of human protein
Conjugate
  • Unconjugated
Molecular weight Observed: 277 kDa
Purification Affinity Purified
Cellular localization Cytoplasmic vesicle . Perikaryon . Golgi apparatus membrane ; Peripheral membrane protein . Cell projection, axon . Cell projection, dendrite . Endoplasmic reticulum membrane ; Peripheral membrane protein . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane . Endosome . Lysosome . Mitochondrion outer membrane ; Peripheral membrane protein . Colocalized with RAB29 along tubular structures emerging from Golgi apparatus (PubMed:23395371). Localizes to endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER) (PubMed:25201882). .
Concentration 1 mg/ml
Formulation PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage -15°C to -25°C/1 year(Do not lower than -25°C)
Catalog no. (Mfr.) WP2279
Main SKU BHA21813558
Antibody

Product Overview

U-Blot® LRRK2 Rabbit Polyclonal Antibody is a rabbit polyclonal antibody from UcallM Biosciences Inc, raised against LRRK2. It has been validated for Immunohistochemistry, Immunofluorescence and reacts with Human, Mouse.

Validated Applications

Target LRRK2
Host Rabbit
Clonality Polyclonal
Isotype IgG
Conjugate Unconjugated
Reactivity Human, Mouse
Applications Immunohistochemistry, Immunofluorescence
Purification Affinity Purified
Specificity LRRK2 Polyclonal Antibody detects endogenous levels of protein.
Molecular Weight Observed: 277 kDa
UniProt / Swiss-Prot Q5S007 (Human) | Q5S006 (Mouse)

Recommended dilutions: IHC 1:50-300;IF 1:50-200

Immunogen / Antigen

Synthesized peptide derived from part region of human protein

Reactivity Notes

Confirmed cross-reactivity: Human, Mouse. Confirm suitability for untested species before use.

Scientific Background

This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8. [provided by RefSeq, Jul 2008]

Safety & Handling

For Research Use Only (RUO). Not for diagnostic or therapeutic use. Store as indicated: -15°C to -25°C/1 year(Do not lower than -25°C)
What applications is this antibody validated for?

This antibody is validated for Immunohistochemistry, Immunofluorescence. Recommended dilutions: IHC 1:50-300;IF 1:50-200

What species does it react with?

Confirmed reactivity: Human, Mouse. Other species should be validated by the user.

Is this antibody conjugated?

Conjugate: Unconjugated.

How should it be stored?

Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)

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