| Field | Specification |
|---|---|
| Target | |
| Alternative names | PMI1;CDG1B;FLJ39201;Mannose 6 phosphate isomerase;Mannose-6-phosphate isomerase;MANNOSEPHOSPHATE ISOMERASE;MGC94106;MPI;MPI_HUMAN;Phosphohexomutase;phosphomannose isomerase 1;Phosphomannose isomerase;PMI;PMI1. |
| Gene ID | |
| Host | |
| Clonality | |
| Reactivity | |
| Applications | |
| Immunogen | Purified recombinant human Mannose Phosphate Isomerase protein fragments expressed in E.coli. |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® Mannose Phosphate Isomerase Mouse Monoclonal Antibody is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against Mannose Phosphate Isomerase. It has been validated for Western Blot, Immunofluorescence and reacts with Human, Rat.
Validated Applications
| Target | Mannose Phosphate Isomerase |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Conjugate | Unconjugated |
| Reactivity | Human, Rat |
| Applications | Western Blot, Immunofluorescence |
| Purification | Affinity Purified |
| Specificity | This antibody detects endogenous levels of Mannose Phosphate Isomerase and does not cross-react with related proteins. |
| Molecular Weight | Observed: 54 kDa |
| UniProt / Swiss-Prot | P34949 (Human) | Q924M7 (Mouse) |
Recommended dilutions: WB 1:1000;ICC 1:300
Immunogen / Antigen
Purified recombinant human Mannose Phosphate Isomerase protein fragments expressed in E.coli.
Reactivity Notes
Confirmed cross-reactivity: Human, Rat. Confirm suitability for untested species before use.
Scientific Background
Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Safety & Handling
This antibody is validated for Western Blot, Immunofluorescence. Recommended dilutions: WB 1:1000;ICC 1:300
Confirmed reactivity: Human, Rat. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
