| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | Calcium uptake protein 1, mitochondrial;Atopy-related autoantigen CALC;ara CALC;Calcium-binding atopy-related autoantigen 1;allergen Hom s 4 |
| Gene ID | |
| Host | |
| Clonality | |
| Reactivity | |
| Applications | |
| Immunogen | Recombinant Protein of MICU1 |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® MICU1 Mouse Monoclonal Antibody (Mix) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against MICU1. It has been validated for Western Blot, Immunofluorescence, Immunohistochemistry and reacts with Human, Mouse, Rat.
Validated Applications
| Target | MICU1 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat |
| Applications | Western Blot, Immunofluorescence, Immunohistochemistry |
| Purification | Affinity Purified |
| Specificity | The antibody detects endogenous MICU1 protein. |
| Molecular Weight | Observed: 55 kDa |
| UniProt / Swiss-Prot | Q9BPX6 (Human) | Q8VCX5 (Mouse) | Q6P6Q9 (Rat) |
Recommended dilutions: WB 1:1000-2000;IHC 1:100-200;IF 1:200
Immunogen / Antigen
Recombinant Protein of MICU1
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat. Confirm suitability for untested species before use.
Scientific Background
This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2013]
Safety & Handling
This antibody is validated for Western Blot, Immunofluorescence, Immunohistochemistry. Recommended dilutions: WB 1:1000-2000;IHC 1:100-200;IF 1:200
Confirmed reactivity: Human, Mouse, Rat. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
