| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | ADMCKD;ADMCKD1;Breast carcinoma associated antigen DF3;Breast carcinoma-associated antigen DF3;CA 15-3;CA15 3;CA15 3 antigen;CA15-3;CA15.3;Cancer antigen 15-3;Carcinoma associated mucin;Carcinoma-associated mucin;CD 227;CD227;DF3 antigen;EMA;Episialin;Epithelial Membrane Antigen;H23 antigen;H23AG;KL 6;KL-6;KL6;Krebs von den Lungen-6;MAM 6;MAM6;MCD;MCKD;MCKD1;Medullary cystic kidney disease 1;autosomal dominant;Medullary cystic kidney disease, autosomal dominant;MUC 1;MUC-1;MUC-1/SEC;MUC-1/X;MUC1;MUC1-alpha;MUC1-beta;MUC1-CT;MUC1-NT;MUC1/ZD;MUC1_HUMAN;Mucin 1;Mucin 1 cell surface associated;Mucin 1 transmembrane;Mucin 1, cell surface associated;Mucin-1 subunit beta;Peanut reactive urinary mucin;Peanut-reactive urinary mucin;PEM;PEMT;Polymorphic epithelial mucin;PUM;Tumor associated epithelial membrane antigen;Tumor associated epithelial mucin;Tumor associated mucin;Tumor-associated epithelial membrane antigen;Tumor-associated mucin |
| Antigen | |
| Cellular Localization | |
| Clonality | |
| Conjugate | |
| Formulation | |
| Gene ID | |
| Host | |
| Immunogen | Synthesized peptide derived from human Epithelial Membrane Antigen(MUC1) AA range: 100-200 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Product Overview
U-Blot® MUC1 (ABT100) Mouse Monoclonal Antibody (WM1292) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against Mucin 1. It has been validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA and reacts with Human.
Validated Applications
| Target | Mucin 1 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | ABT100 |
| Isotype | IgG1, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human |
| Applications | Immunohistochemistry, Western Blot, Immunofluorescence, ELISA |
| Purification | Protein G |
| Specificity | The antibody can specifically recognize human MUC1 protein. In western blotting of NIH3T3 cell lysate, there shows a 122 kDa band detected by the antibody. |
| Molecular Weight | Calculated: 122 kDa | Observed: 122 kDa |
| UniProt / Swiss-Prot | P15941 (Human) |
Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Immunogen / Antigen
Synthesized peptide derived from human Epithelial Membrane Antigen(MUC1) AA range: 100-200
Reactivity Notes
Confirmed cross-reactivity: Human. Confirm suitability for untested species before use.
Scientific Background
MUC1 is a type I transmembrane protein with a molecular weight of 450 kDa. One of the characteristics of glandular epithelial tissue is the synthesis and secretion of MUC1. It plays an important role in epithelial renewal and differentiation, maintaining epithelial integrity and carcinogenesis and metastasis. Under normal conditions, it is mainly expressed in a variety of tissues and organs, epithelial cells near the lumen or glandular cavity, showing apical expression and polar distribution. It is also expressed in T cells, B cells and dendritic cells of hematopoietic system. It is mainly used to identify tumors of epithelial origin.
Safety & Handling
This antibody is validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA. Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Confirmed reactivity: Human. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone ABT100.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
