| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | Mucin-4;MUC-4;Ascites sialoglycoprotein;ASGP;Pancreatic adenocarcinoma mucin;Testis mucin;Tracheobronchial mucin;[Cleaved into: Mucin-4 alpha chain;Ascites sialoglycoprotein 1;ASGP-1;Mucin-4 beta chain;Ascites sialoglycoprotein 2;ASGP-2;] |
| Gene ID | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | Synthesized peptide derived from human MUC4 AA range: 2000-2100 |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® MUC4 (ABT199) Mouse Monoclonal Antibody is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against MUC4. It has been validated for Immunohistochemistry, Immunofluorescence, ELISA and reacts with Human.
Validated Applications
| Target | MUC4 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | ABT199 |
| Isotype | IgG2a, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human |
| Applications | Immunohistochemistry, Immunofluorescence, ELISA |
| Purification | Affinity Purified |
| Specificity | The antibody can specifically recognize human MUC4 protein, and has no cross reaction wit MUC2, MUC5AC, MUC6 proteins. |
| Molecular Weight | Calculated: 231 kDa |
| UniProt / Swiss-Prot | Q99102 (Human) |
Recommended dilutions: IHC 1:200-400;IF 1:50-200;ELISA 1:500-5000
Immunogen / Antigen
Synthesized peptide derived from human MUC4 AA range: 2000-2100
Reactivity Notes
Confirmed cross-reactivity: Human. Confirm suitability for untested species before use.
Scientific Background
The major constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervix, are highly glycosylated proteins called mucins. These glycoproteins play important roles in the protection of the epithelial cells and have been implicated in epithelial renewal and differentiation. This gene encodes an integral membrane glycoprotein found on the cell surface, although secreted isoforms may exist. At least two dozen transcript variants of this gene have been found, although for many of them the full-length transcript has not been determined or they are found only in tumor tissues. This gene contains a region in the coding sequence which has a variable number (>100) of 48 nt tandem repeats. [provided by RefSeq, Jul 2008]
Safety & Handling
This antibody is validated for Immunohistochemistry, Immunofluorescence, ELISA. Recommended dilutions: IHC 1:200-400;IF 1:50-200;ELISA 1:500-5000
Confirmed reactivity: Human. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone ABT199.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
