| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | Myeloid differentiation primary response protein MyD88 |
| Gene ID | |
| Host | |
| Clone | |
| Clonality | |
| Reactivity | |
| Applications | |
| Immunogen | Synthesized peptide derived from human Myd88 |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Concentration | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® MyD88 Mouse Monoclonal Antibody (2H12) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against MyD88. It has been validated for Immunohistochemistry and reacts with Human, Mouse, Rat.
Validated Applications
| Target | MyD88 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 2H12 |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat |
| Applications | Immunohistochemistry |
| Purification | Affinity Purified |
| Specificity | This antibody detects endogenous levels of Myd88 at Human, Mouse,Rat |
| Molecular Weight | Observed: 33 kDa |
| UniProt / Swiss-Prot | Q99836 (Human) | P22366 (Mouse) | Q6Y1S1 (Rat) |
Recommended dilutions: IHC 1:50-200
Immunogen / Antigen
Synthesized peptide derived from human Myd88
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat. Confirm suitability for untested species before use.
Scientific Background
This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
Safety & Handling
This antibody is validated for Immunohistochemistry. Recommended dilutions: IHC 1:50-200
Confirmed reactivity: Human, Mouse, Rat. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone 2H12.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
