| Field | Specification |
|---|---|
| Target | |
| Host | |
| Clone | |
| Clonality | |
| Reactivity | |
| Applications | |
| Immunogen | Synthetic Peptide of Myosin Heavy Chain |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® Myosin Heavy Chain Mouse Monoclonal Antibody (11C2) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against Myosin Heavy Chain. It has been validated for Immunofluorescence and reacts with Human, Mouse, Rat, Drosophila.
Validated Applications
| Target | Myosin Heavy Chain |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 11C2 |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat, Drosophila |
| Applications | Immunofluorescence |
| Purification | Affinity Purified |
| Specificity | The antibody detects endogenous MHC proteins. |
| Molecular Weight | Observed: 220 kDa |
| UniProt / Swiss-Prot | P05976;P08590;P10916;P11055;P12829;P12882;P13533;P60660;Q02045 (Human) |
Recommended dilutions: IF 1:100
Immunogen / Antigen
Synthetic Peptide of Myosin Heavy Chain
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat, Drosophila. Confirm suitability for untested species before use.
Scientific Background
Skeletal muscle Myosin or myosin II is the motor protein that generates force to drive muscle contraction. It is a 520 kDa hexamer comprised of two heavy chains and four light chains. Myosin heavy chain is 220 kDa in size and consists of a long coiled-coil domain tail that mediates dimerization of the two heavy chains and a globular head region that mediates ATP-dependent sliding of actin filaments. Myosin heavy chain can be proteolytically cleaved to produce heavy meromyosin, which includes the S1 motor domain (head region) and first third of the coiled coil domain, and light meromyosin, which includes the C-terminal two thirds of the coiled coil domain.
Safety & Handling
This antibody is validated for Immunofluorescence. Recommended dilutions: IF 1:100
Confirmed reactivity: Human, Mouse, Rat, Drosophila. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone 11C2.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
