| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | L1CAM;CAML1;MIC5;Neural cell adhesion molecule L1;N-CAM-L1;NCAM-L1;CD antigen CD171 |
| Gene ID | |
| Host | |
| Clonality | |
| Reactivity | |
| Applications | |
| Immunogen | Purified recombinant human NCAM-L1 (N-terminus) protein fragments expressed in E.coli. |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® NCAM-L1 Mouse Monoclonal Antibody is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against NCAM-L1. It has been validated for Western Blot and reacts with Human, Mouse, Rat, Dog, Rabbit.
Validated Applications
| Target | NCAM-L1 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat, Dog, Rabbit |
| Applications | Western Blot |
| Purification | Affinity Purified |
| Specificity | NCAM-L1 Monoclonal Antibody detects endogenous levels of NCAM-L1 protein. |
| Molecular Weight | Calculated: 140 kDa |
| UniProt / Swiss-Prot | P32004 (Human) | P11627 (Mouse) | Q05695 (Rat) |
Recommended dilutions: WB 1:1000-1:2000;Not yet tested in other applications.
Immunogen / Antigen
Purified recombinant human NCAM-L1 (N-terminus) protein fragments expressed in E.coli.
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat, Dog, Rabbit. Confirm suitability for untested species before use.
Scientific Background
The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons. [provided by RefSeq, May 2013]
Safety & Handling
This antibody is validated for Western Blot. Recommended dilutions: WB 1:1000-1:2000;Not yet tested in other applications.
Confirmed reactivity: Human, Mouse, Rat, Dog, Rabbit. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
