| Field | Specification |
|---|---|
| Target | |
| Alternative names | DKFZp686C01211;DNA binding factor KBF1;DNA binding factor KBF1 EBP1;DNA-binding factor KBF1;EBP 1;EBP-1;EBP1;KBF1;MGC54151;NF kappa B;NF kappaB;NF kappabeta;NF kB1;NFkappaB;NFKB 1;NFKB p105;NFKB p50;Nfkb1;NFKB1_HUMAN;Nuclear factor kappa B DNA binding subunit;Nuclear factor kappa-B, subunit 1;Nuclear factor NF kappa B p105 subunit;Nuclear factor NF kappa B p50 subunit;Nuclear factor NF-kappa-B p50 subunit;Nuclear factor of kappa light polypeptide gene enhancer in B cells 1;Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1;p105;p50;p84/NF-kappa-B1 p98. |
| Gene ID | |
| Host | |
| Clonality | |
| Reactivity | |
| Applications | |
| Immunogen | Recombinant human NF-κB1 p105/p50 protein. |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® NFKB1 Mouse Monoclonal Antibody is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against NFKB1. It has been validated for Western Blot and reacts with Human.
Validated Applications
| Target | NFKB1 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Conjugate | Unconjugated |
| Reactivity | Human |
| Applications | Western Blot |
| Purification | Affinity Purified |
| Specificity | This antibody detects endogenous levels of NF-κB1 p105/p50 and does not cross-react with related proteins. |
| Molecular Weight | Calculated: 105 kDa |
| UniProt / Swiss-Prot | P19838 (Human) | P25799 (Mouse) |
Recommended dilutions: WB 1:500
Immunogen / Antigen
Recombinant human NF-κB1 p105/p50 protein.
Reactivity Notes
Confirmed cross-reactivity: Human. Confirm suitability for untested species before use.
Scientific Background
nuclear factor kappa B subunit 1(NFKB1) Homo sapiens This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isof
Safety & Handling
This antibody is validated for Western Blot. Recommended dilutions: WB 1:500
Confirmed reactivity: Human. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
