| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | BAPX 2;BAPX2;Homeobox protein NK-3 homolog A;Homeobox protein Nkx 3.1;Homeobox protein Nkx-3.1;Homeobox protein Nkx3.1;NK homeobox;Drosophila;family 3 A;NK homeobox family 3 A;NK homeobox, family 3, member A;NK3 homeobox 1;NK3 transcription factor homolog A;NK3 transcription factor related locus 1;NKX 3;Nkx 3.1;NKX 3A;NKX3 1;NKX3;Nkx3-1;NKX3.1;Nkx3.1, Mouse, homolog of;NKX31_HUMAN;NKX3A |
| Antigen | |
| Cellular Localization | |
| Clonality | |
| Conjugate | |
| Formulation | |
| Gene ID | |
| Host | |
| Immunogen | Synthesized peptide derived from human protein. AA range:1-100 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Product Overview
U-Blot® NKX3.1 (ABT267) Mouse Monoclonal Antibody (WM1465) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against NKX3.1. It has been validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA and reacts with Human.
Validated Applications
| Target | NKX3.1 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | ABT267 |
| Isotype | IgG1, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human |
| Applications | Immunohistochemistry, Western Blot, Immunofluorescence, ELISA |
| Purification | Protein G |
| Specificity | The antibody can specifically recognize human NKX3.1 protein. |
| Molecular Weight | Calculated: 26 kDa | Observed: 32 kDa |
| UniProt / Swiss-Prot | Q99801 (Human) | P97436 (Mouse) |
Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Immunogen / Antigen
Synthesized peptide derived from human protein. AA range:1-100
Reactivity Notes
Confirmed cross-reactivity: Human. Confirm suitability for untested species before use.
Scientific Background
NKX3.1 is a nuclear transcription factor and a negative regulator of the growth of prostatic epithelial cells. Its mRNA transcription level is regulated by androgens and plays an important role in the occurrence and differentiation of prostate organs and the maintenance of the function of mature organs. NKX3.1 has high sensitivity and specificity in benign prostatic hyperplasia and prostate cancer, and can be used as one of the specific markers to distinguish prostate cancer, benign prostatic hyperplasia and non prostate cancer. It is also expressed in mucous glands of testis, ureter and pulmonary bronchus.
Safety & Handling
This antibody is validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA. Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Confirmed reactivity: Human. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone ABT267.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
