| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | AIS;Amplified in squamous cell carcinoma;B;p51A;B;p51B;Chronic ulceRative stomatitis protein;CUSP;DN p63 alpha 1;DNp63;EEC3;id:ibd3516;KeRatinocyte transcription factor;KeRatinocyte transcription factor KET;KET;LMS;MGC115972;MGC192897;NBP;OFC8;OTTHUMP00000209732;OTTHUMP00000209733;OTTHUMP00000209734;OTTHUMP00000209735;OTTHUMP00000209737;OTTHUMP00000209738;OTTHUMP00000209739;OTTHUMP00000209740;OTTHUMP00000209741;OTTHUMP00000209742;OTTHUMP00000209743;OTTHUMP00000209744;p40;p51;P51/P63;p53-related protein p63;p53CP;p63;P63_HUMAN;p73H;p73L;RHS;SHFM4;TAp63alpha;TP53CP;TP53L;TP63;TP73L;Transformation related protein 63;Transformation-related protein 63;Trp53rp1;Trp63;Tumor protein 63;Tumor protein p53-competing protein;Tumor protein p53-like;Tumor protein p63;Tumor protein p63 deltaN isoform delta;Tumor protein p73;Tumor protein p73-like |
| Antigen | |
| Cellular Localization | |
| Clonality | |
| Conjugate | |
| Formulation | |
| Gene ID | |
| Host | |
| Immunogen | Synthesized peptide derived from human p63 AA range: 1-100 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Product Overview
U-Blot® p40 (ABT020) Mouse Monoclonal Antibody (WM1458) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against p40/p63. It has been validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA and reacts with Human, Mouse.
Validated Applications
| Target | p40/p63 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | ABT020 |
| Isotype | IgG2b, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse |
| Applications | Immunohistochemistry, Western Blot, Immunofluorescence, ELISA |
| Purification | Protein G |
| Specificity | The antibody can specifically recognize human P40(ΔNp63) protein, and TAp63 dose not respond. |
| Molecular Weight | Calculated: 77 kDa | Observed: 77 kDa,69 kDa |
| UniProt / Swiss-Prot | Q9H3D4 (Human) |
Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Immunogen / Antigen
Synthesized peptide derived from human p63 AA range: 1-100
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse. Confirm suitability for untested species before use.
Scientific Background
P40 (△ Np63) is one of the subtypes of p63 protein and the main p63 isoform in basal cells / progenitor cells. It is expressed in urothelial cells and squamous cells, myoepithelial cells of breast, sweat gland and salivary gland, and basal cells of prostate. P40 has a high sensitivity similar to p63 in lung squamous cell carcinoma, but it is rarely expressed in lung adenocarcinoma, so P40 is used in the differential diagnosis of lung squamous cell carcinoma and lung adenocarcinoma.
Safety & Handling
This antibody is validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA. Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Confirmed reactivity: Human, Mouse. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone ABT020.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
