| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | RPS6KB2;STK14B;Ribosomal protein S6 kinase beta-2;S6K-beta-2;S6K2;70 kDa ribosomal protein S6 kinase 2;P70S6K2;p70-S6K 2;S6 kinase-related kinase;SRK;Serine/threonine-protein kinase 14B;p70 ribosomal S6 kinase beta;S6K-beta;p70 |
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| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Conjugate | |
| Molecular weight | |
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Product Overview
U-Blot® p70 S6 kinase β (Phospho Ser371) Rabbit Monoclonal Antibody is a rabbit monoclonal antibody from UcallM Biosciences Inc, raised against P70S6k. Recognizes Phospho (Ser371). It has been validated for Western Blot, Immunohistochemistry, Immunofluorescence, ELISA and reacts with Human, Mouse, Rat.
Validated Applications
| Target | P70S6k |
|---|---|
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | PT0919R |
| Isotype | IgG, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat |
| Applications | Western Blot, Immunohistochemistry, Immunofluorescence, ELISA |
| Purification | Protein A |
| Specificity | Phospho-p70 S6 kinase β (S371) Antibody detects endogenous levels of p70 S6 kinase β protein only when phosphorylated at S371.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):DSpDD |
| Molecular Weight | Calculated: 53 kDa | Observed: 60 kDa |
| UniProt / Swiss-Prot | Q9UBS0 (Human) | Q9Z1M4 (Mouse) |
Recommended dilutions: IHC 1:500-1:2000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000
Immunogen / Antigen
Ribosomal protein S6 kinase beta-2
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat. Confirm suitability for untested species before use.
Scientific Background
ribosomal protein S6 kinase B2(RPS6KB2) Homo sapiens This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains a kinase catalytic domain and phosphorylates the S6 ribosomal protein and eukaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation. [provided by RefSeq, Jan 2015]
Safety & Handling
This antibody is validated for Western Blot, Immunohistochemistry, Immunofluorescence, ELISA. Recommended dilutions: IHC 1:500-1:2000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000
Confirmed reactivity: Human, Mouse, Rat. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone PT0919R.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
