| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | RPS6KB1 |
| Gene ID | |
| Host | |
| Clone | |
| Clonality | |
| Reactivity | |
| Applications | |
| Immunogen | Recombinant Protein of P70 S6 Kinase of RPS6KB1 |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Concentration | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® P70 S6 Kinase Mouse Monoclonal Antibody (1C7) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against p70 S6 kinase α. It has been validated for Immunohistochemistry, Immunofluorescence and reacts with Human, Rat, Mouse.
Validated Applications
| Target | p70 S6 kinase α |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 1C7 |
| Conjugate | Unconjugated |
| Reactivity | Human, Rat, Mouse |
| Applications | Immunohistochemistry, Immunofluorescence |
| Purification | Affinity Purified |
| Specificity | P70 S6 Kinase protein detects endogenous levels of RPS6KB1 |
| Molecular Weight | Observed: 70,85 kDa |
| UniProt / Swiss-Prot | P23443 (Human) | Q8BSK8 (Mouse) | P67999 (Rat) |
Recommended dilutions: IHC 1:100-200;IF 1:50-200
Immunogen / Antigen
Recombinant Protein of P70 S6 Kinase of RPS6KB1
Reactivity Notes
Confirmed cross-reactivity: Human, Rat, Mouse. Confirm suitability for untested species before use.
Scientific Background
ribosomal protein S6 kinase B1(RPS6KB1) Homo sapiens This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013]
Safety & Handling
This antibody is validated for Immunohistochemistry, Immunofluorescence. Recommended dilutions: IHC 1:100-200;IF 1:50-200
Confirmed reactivity: Human, Rat, Mouse. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone 1C7.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
