| Field | Specification |
|---|---|
| Alternative Names | Kac |
| Clonality | |
| Conjugate | |
| Formulation | |
| Host | |
| Immunogen | polypeptide |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Product Overview
U-Blot® Pan-Acetyllysine Rabbit pAb (peptide immunogen) is a polyclonal antibody raised in Rabbit that specifically recognizes Acetyllysine (Lysine acetylation [Lys(K)]). It is designed for detection and analysis of the Lysine acetylation [Lys(K)] post-translational modification across research applications.
Acetyllysine (abbreviated as Kac) is a classic and widespread post-translational modification of lysine acetylation. This modification covalently adds an acetyl group to the side-chain amino group of lysine residues, altering the charge and structure of proteins to regulate their functions. Lysine acetylation is an important epigenetic marker on histones, involved in chromatin remodeling and gene transcription regulation. It also widely exists in non-histone proteins such as metabolic enzymes, signaling proteins, and transcription factors, playing essential roles in cellular metabolism, signal transduction, cell cycle progression, and DNA repair. Dysregulation of lysine acetylation is closely associated with the development of cancer, metabolic diseases, neurodegenerative diseases, and other disorders.
Validated Applications
| Application | Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry |
|---|---|
| Recommended Dilution | WB 1:1000-1:2000, IHC-P 1:100-1:200, ICC/IF 1:100-1:200, FC 1:100-1:200 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Reactivity | Species Independent |
| Conjugate | Unconjugated |
| Purification | Protein A |
| Molecular Weight | Calculated: Multiple | Observed: Multiple |
Immunogen / Antigen
polypeptide
Reactivity Notes
This antibody shows reactivity with Species Independent. It targets the Lysine acetylation [Lys(K)] modification and is suitable for Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry.
Safety & Handling
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Explore other UcallM Biosciences post-translational modification antibodies available through BioHippo.
It is validated for Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry. Recommended dilutions: WB 1:1000-1:2000, IHC-P 1:100-1:200, ICC/IF 1:100-1:200, FC 1:100-1:200.
Use WB 1:1000-1:2000, IHC-P 1:100-1:200, ICC/IF 1:100-1:200, FC 1:100-1:200. Optimal dilution should be determined empirically for your sample and detection system.
This is a pan-modification antibody recognizing Acetyllysine (Lysine acetylation [Lys(K)]); reactivity: Species Independent.
The polyclonal antibody (Rabbit host) was raised against polypeptide.
This product is supplied unconjugated. Contact BioHippo for custom conjugation or format options.
Store at -20°C. Avoid repeated freeze-thaw cycles | Stable for 12 months from date of receipt / reconstitution.
Customization & Add-ons: Can't find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
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