| Field | Specification |
|---|---|
| Alternative Names | Kce |
| Clonality | |
| Conjugate | |
| Formulation | |
| Host | |
| Immunogen | polypeptide |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Product Overview
U-Blot® Pan-Carboxyethyllysine Rabbit mAb is a recombinant monoclonal antibody raised in Rabbit that specifically recognizes Carboxyethyllysine (Lysine carboxyethylation [Lys(K)]). It is designed for detection and analysis of the Lysine carboxyethylation [Lys(K)] post-translational modification across research applications.
Carboxyethyl lysine (Kce) is an important member of Advanced Glycation End Products (AGEs), which is a non-enzymatic post-translational modification product of protein lysine residues. It is mainly formed by the non-enzymatic glycooxidation reaction between methylglyoxal (MGO), a by-product of cellular metabolism, and the ε-amino group of lysine side chains, and can also be induced by the autoxidation and cleavage of monosaccharides such as glucose. Kce modification can change the structure and function of proteins, activate downstream signals such as inflammation and oxidative stress by binding to RAGE receptors, and participate in the pathological processes related to diabetes, obesity, atherosclerosis, neurodegenerative diseases and aging, serving as an important molecular marker of metabolic stress and long-term oxidative damage.
Validated Applications
| Application | Western Blot |
|---|---|
| Recommended Dilution | WB 1:500-1000 |
| Host | Rabbit |
| Clonality | Recombinant Monoclonal |
| Isotype | IgG |
| Reactivity | Human, Mouse, Rat |
| Conjugate | Unconjugated |
| Purification | Protein A |
| Molecular Weight | Calculated: Multiple | Observed: Multiple |
Immunogen / Antigen
polypeptide
Reactivity Notes
This antibody shows reactivity with Human, Mouse, Rat. It targets the Lysine carboxyethylation [Lys(K)] modification and is suitable for Western Blot.
Safety & Handling
Related Products
Explore other UcallM Biosciences post-translational modification antibodies available through BioHippo.
It is validated for Western Blot. Recommended dilutions: WB 1:500-1000.
Use WB 1:500-1000. Optimal dilution should be determined empirically for your sample and detection system.
This is a pan-modification antibody recognizing Carboxyethyllysine (Lysine carboxyethylation [Lys(K)]); reactivity: Human, Mouse, Rat.
The recombinant monoclonal antibody (Rabbit host) was raised against polypeptide.
This product is supplied unconjugated. Contact BioHippo for custom conjugation or format options.
Store at -20°C. Avoid repeated freeze-thaw cycles | Stable for 12 months from date of receipt / reconstitution.
Customization & Add-ons: Can't find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
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