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Product Overview
U-Blot® Pan-Leucyllysine Rabbit mAb is a monoclonal antibody raised in Rabbit that specifically recognizes Leucyllysine (Lysine aminoacylation/acylation [Lys(K)]). It is designed for detection and analysis of the Lysine aminoacylation/acylation [Lys(K)] post-translational modification across research applications.
Leucyllysine (abbreviated as Kleu) is a novel aminoacylation-type post-translational modification occurring on lysine residues of proteins. This modification is formed by covalently attaching a leucyl group to the side chain amino group of lysine, which alters the charge, structure, and interaction properties of proteins. Kleu is widely distributed on histones and various functional proteins, and participates in key biological processes including gene transcription regulation, cellular metabolism, and protein homeostasis. It plays important roles in metabolic regulation, stress response, and related disease research, serving as an emerging target in the field of protein modification.
Validated Applications
| Application | Western Blot |
|---|---|
| Host | Rabbit |
| Clonality | Monoclonal |
| Conjugate | Unconjugated |
| Molecular Weight | Calculated: Multiple | Observed: Multiple |
Reactivity Notes
This antibody shows reactivity with multiple species. It targets the Lysine aminoacylation/acylation [Lys(K)] modification and is suitable for Western Blot.
Safety & Handling
Related Products
Explore other UcallM Biosciences post-translational modification antibodies available through BioHippo.
It is validated for Western Blot. Recommended dilutions: application-dependent (see datasheet).
Use application-dependent (see datasheet). Optimal dilution should be determined empirically for your sample and detection system.
This is a pan-modification antibody recognizing Leucyllysine (Lysine aminoacylation/acylation [Lys(K)]); reactivity: multiple species.
The monoclonal antibody (Rabbit host) was raised against a synthetic peptide corresponding to the modified residue.
This product is supplied unconjugated. Contact BioHippo for custom conjugation or format options.
Store at -20°C; avoid repeated freeze-thaw cycles.
Customization & Add-ons: Can't find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
