| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | PARP1;ADPRT;PPOL;Poly [ADP-ribose] polymerase 1;PARP-1;ADP-ribosyltransferase diphtheria toxin-like 1;ARTD1;NAD;+;ADP-ribosyltransferase 1;ADPRT 1;Poly[ADP-ribose] synthase 1 |
| Gene ID | |
| Host | |
| Clonality | |
| Reactivity | |
| Applications | |
| Immunogen | Synthetic peptide of human PARP-1, conjugated to KLH. |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® PARP-1 Mouse Monoclonal Antibody is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against PARP. It has been validated for Western Blot, Flow Cytometry, ELISA and reacts with Human.
Validated Applications
| Target | PARP |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Conjugate | Unconjugated |
| Reactivity | Human |
| Applications | Western Blot, Flow Cytometry, ELISA |
| Purification | Affinity Purified |
| Specificity | PARP-1 Monoclonal Antibody detects endogenous levels of PARP-1 protein. |
| Molecular Weight | Calculated: 113 kDa |
| UniProt / Swiss-Prot | P09874 (Human) | P11103 (Mouse) |
Recommended dilutions: WB 1:500-1:2000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.
Immunogen / Antigen
Synthetic peptide of human PARP-1, conjugated to KLH.
Reactivity Notes
Confirmed cross-reactivity: Human. Confirm suitability for untested species before use.
Scientific Background
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]
Safety & Handling
This antibody is validated for Western Blot, Flow Cytometry, ELISA. Recommended dilutions: WB 1:500-1:2000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.
Confirmed reactivity: Human. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
