| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | PDGFRA |
| Gene ID | |
| Host | |
| Clone | |
| Clonality | |
| Reactivity | |
| Applications | |
| Immunogen | Synthetic Peptide of PDGFRα at AA range of 1010-1090 |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Concentration | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® PDGFRα Mouse Monoclonal Antibody (7A3) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against PDGF Receptor α. It has been validated for Immunofluorescence, Immunohistochemistry and reacts with Human, Rat, Mouse.
Validated Applications
| Target | PDGF Receptor α |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 7A3 |
| Conjugate | Unconjugated |
| Reactivity | Human, Rat, Mouse |
| Applications | Immunofluorescence, Immunohistochemistry |
| Purification | Affinity Purified |
| Specificity | PDGFRα protein detects endogenous levels of PDGFRA |
| Molecular Weight | Observed: 180 kDa |
| UniProt / Swiss-Prot | P16234 (Human) | P26618 (Mouse) | P20786 (Rat) |
Recommended dilutions: IF 1:50-200;IHC 1:100-200
Immunogen / Antigen
Synthetic Peptide of PDGFRα at AA range of 1010-1090
Reactivity Notes
Confirmed cross-reactivity: Human, Rat, Mouse. Confirm suitability for untested species before use.
Scientific Background
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012]
Safety & Handling
This antibody is validated for Immunofluorescence, Immunohistochemistry. Recommended dilutions: IF 1:50-200;IHC 1:100-200
Confirmed reactivity: Human, Rat, Mouse. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone 7A3.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
