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Product Overview
U-Blot® PGC1 β Rabbit Monoclonal Antibody is a rabbit monoclonal antibody from UcallM Biosciences Inc, raised against PGC1 β. It has been validated for Western Blot, Immunoprecipitation, ELISA and reacts with Human, Mouse, Rat.
Validated Applications
| Target | PGC1 β |
|---|---|
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | PT0194R |
| Isotype | IgG, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat |
| Applications | Western Blot, Immunoprecipitation, ELISA |
| Purification | Protein A |
| Specificity | Endogenous |
| Molecular Weight | Calculated: 113 kDa | Observed: 113 kDa |
| UniProt / Swiss-Prot | Q86YN6 (Human) | Q8VHJ7 (Mouse) | Q811R2 (Rat) |
Recommended dilutions: WB 1:1000-1:5000;ELISA 1:5000-1:20000;IP 1:50-1:200
Immunogen / Antigen
PPARGC1B PERC PGC1 PGC1B PPARGC1
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat. Confirm suitability for untested species before use.
Scientific Background
The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
Safety & Handling
This antibody is validated for Western Blot, Immunoprecipitation, ELISA. Recommended dilutions: WB 1:1000-1:5000;ELISA 1:5000-1:20000;IP 1:50-1:200
Confirmed reactivity: Human, Mouse, Rat. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone PT0194R.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
