| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | MAPT, MAPTL, MTBT1 |
| Gene ID | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | polypeptide |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® Phospho-Tau (Ser199) Rabbit mAb is a recombinant monoclonal antibody raised in Rabbit that specifically recognizes Phospho-Tau (Ser199) (Phosphorylation [Ser199]). It is designed for detection and analysis of the Phosphorylation [Ser199] post-translational modification across research applications.
Promotes microtubule assembly and stability and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Validated Applications
| Application | Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry |
|---|---|
| Recommended Dilution | WB 1:1000-1:3000, IHC-P 1:200-1:1000, ICC/IF 1:50, FC 1:50-1:100 |
| Host | Rabbit |
| Clonality | Recombinant Monoclonal |
| Isotype | IgG |
| Reactivity | Human, Mouse, Rat |
| Conjugate | Unconjugated |
| Purification | Protein A |
| Molecular Weight | Calculated: 79 kDa | Observed: 55 kDa |
Immunogen / Antigen
polypeptide
Reactivity Notes
This antibody shows reactivity with Human, Mouse, Rat. It targets the Phosphorylation [Ser199] modification and is suitable for Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry.
Safety & Handling
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It is validated for Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry. Recommended dilutions: WB 1:1000-1:3000, IHC-P 1:200-1:1000, ICC/IF 1:50, FC 1:50-1:100.
Use WB 1:1000-1:3000, IHC-P 1:200-1:1000, ICC/IF 1:50, FC 1:50-1:100. Optimal dilution should be determined empirically for your sample and detection system.
This is a pan-modification antibody recognizing Phospho-Tau (Ser199) (Phosphorylation [Ser199]); reactivity: Human, Mouse, Rat.
The recombinant monoclonal antibody (Rabbit host) was raised against polypeptide.
This product is supplied unconjugated. Contact BioHippo for custom conjugation or format options.
Store at -20°C. Avoid repeated freeze-thaw cycles | Stable for 12 months from date of receipt / reconstitution.
Customization & Add-ons: Can't find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
