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| Immunogen | Synthesized peptide derived from human PKC AA range: 450-550 |
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Product Overview
U-Blot® PKC (PTR1190) Mouse Monoclonal Antibody is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against PRKCA. It has been validated for Western Blot, Immunofluorescence, ELISA and reacts with Human, Mouse, Rat, Rabbit, Bovine.
Validated Applications
| Target | PRKCA |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | PTR1190 |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat, Rabbit, Bovine |
| Applications | Western Blot, Immunofluorescence, ELISA |
| Purification | Protein G |
| Specificity | This antibody detects endogenous levels of PKC protein. |
| Molecular Weight | Observed: 80 kDa |
| UniProt / Swiss-Prot | P17252;P05771;P24723;P05129 (Human) | P20444 (Mouse) |
Recommended dilutions: WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Immunogen / Antigen
Synthesized peptide derived from human PKC AA range: 450-550
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat, Rabbit, Bovine. Confirm suitability for untested species before use.
Scientific Background
protein kinase C alpha(PRKCA) Homo sapiens Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes. [provided by RefSeq, Jul 2
Safety & Handling
This antibody is validated for Western Blot, Immunofluorescence, ELISA. Recommended dilutions: WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Confirmed reactivity: Human, Mouse, Rat, Rabbit, Bovine. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone PTR1190.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
