U-Blot® PPARBP (Phospho Thr1032) Rabbit Polyclonal Antibody

SKU:BHA21805192
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UcallM Biosciences Inc
UcallM Biosciences Inc
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Overview
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Anti-TRAP220 antibody (Rabbit host, polyclonal, Unconjugated). Validated for Immunohistochemistry, Western Blot with reactivity to Human, Mouse.
Clonality Polyclonal
Host Rabbit
Reactivity Human, Mouse
Conjugate Unconjugated
Applications Immunohistochemistry, Western Blot
Options selector
Catalog no. Size
WP10776-50 50 uL
WP10776-100 100 uL
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 50 uL
  • Lead time: options listed in "Availability Content"; other statuses may take longer.
  • Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
  • Shipping: cold-chain shipment (typically with ice packs).
  • Upon receipt: store at recommended temperature as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Target TRAP220
Antigen
  • Mediator of RNA polymerase II transcription subunit 1 (Activator-recruited cofactor 205 kDa component) (ARC205) (Mediator complex subunit 1) (Peroxisome proliferator-activated receptor-binding protein) (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TR-interacting protein 2) (TRIP-2) (Vitamin D receptor-interacting protein complex component DRIP205) (p53 regulatory protein RB18A)
Alternative names Mediator of RNA polymerase II transcription subunit 1;Activator-recruited cofactor 205 kDa component;ARC205;Mediator complex subunit 1;Peroxisome proliferator-activated receptor-binding protein;PBP;PPAR-binding protein;Thyroid hormone receptor-associated protein complex 220 kDa component;Trap220;Thyroid receptor-interacting protein 2;TR-interacting protein 2;TRIP-2;Vitamin D receptor-interacting protein complex component DRIP205;p53 regulatory protein RB18A
Gene ID 5469 (Human) | 19014 (Mouse)
Host Rabbit
Clonality
  • Polyclonal
Reactivity
  • Human
  • Mouse
Applications
  • Immunohistochemistry
  • Western Blot
Immunogen Synthesized peptide derived from human PPARBP (Phospho Thr1032)
Conjugate
  • Unconjugated
Molecular weight Calculated: 174 kDa
Purification Affinity Purified
Cellular localization Nucleus . A subset of the protein may enter the nucleolus subsequent to phosphorylation by MAPK1 or MAPK3.
Concentration 1 mg/ml
Formulation PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage -15°C to -25°C/1 year(Do not lower than -25°C)
Catalog no. (Mfr.) WP10776
Main SKU BHA21805192
Antibody

Product Overview

U-Blot® PPARBP (Phospho Thr1032) Rabbit Polyclonal Antibody is a rabbit polyclonal antibody from UcallM Biosciences Inc, raised against TRAP220. Recognizes Phospho. It has been validated for Immunohistochemistry, Western Blot and reacts with Human, Mouse.

Validated Applications

Target TRAP220
Host Rabbit
Clonality Polyclonal
Conjugate Unconjugated
Reactivity Human, Mouse
Applications Immunohistochemistry, Western Blot
Purification Affinity Purified
Specificity This antibody detects endogenous levels of PPARBP (Phospho Thr1032) Rabbit pAb at Human, Mouse
Molecular Weight Calculated: 174 kDa
UniProt / Swiss-Prot Q15648 (Human) | Q925J9 (Mouse)

Recommended dilutions: WB 1:500-2000;IHC 1:50-200

Immunogen / Antigen

Synthesized peptide derived from human PPARBP (Phospho Thr1032)

Reactivity Notes

Confirmed cross-reactivity: Human, Mouse. Confirm suitability for untested species before use.

Scientific Background

mediator complex subunit 1(MED1) Homo sapiens The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. It also regulates p53-dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize. [provided by RefSeq, Jul 2008]

Safety & Handling

For Research Use Only (RUO). Not for diagnostic or therapeutic use. Store as indicated: -15°C to -25°C/1 year(Do not lower than -25°C)
What applications is this antibody validated for?

This antibody is validated for Immunohistochemistry, Western Blot. Recommended dilutions: WB 1:500-2000;IHC 1:50-200

What species does it react with?

Confirmed reactivity: Human, Mouse. Other species should be validated by the user.

Is this antibody conjugated?

Conjugate: Unconjugated.

How should it be stored?

Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)

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