| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | PRMT1;HMT2;HRMT1L2;IR1B4;Protein arginine N-methyltransferase 1;Histone-arginine N-methyltransferase PRMT1;Interferon receptor 1-bound protein 4 |
| Gene ID | |
| Host | |
| Clonality | |
| Reactivity | |
| Applications | |
| Immunogen | Purified recombinant human PRMT1 protein fragments expressed in E.coli. |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® PRMT1 Mouse Monoclonal Antibody is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against PRMT1. It has been validated for Western Blot and reacts with Human, Mouse, Rat, Dog, Rabbit.
Validated Applications
| Target | PRMT1 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat, Dog, Rabbit |
| Applications | Western Blot |
| Purification | Affinity Purified |
| Specificity | PRMT1 Monoclonal Antibody detects endogenous levels of PRMT1 protein. |
| Molecular Weight | Calculated: 42 kDa |
| UniProt / Swiss-Prot | Q99873 (Human) | Q9JIF0 (Mouse) | Q63009 (Rat) |
Recommended dilutions: WB 1:1000-1:2000;Not yet tested in other applications.
Immunogen / Antigen
Purified recombinant human PRMT1 protein fragments expressed in E.coli.
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat, Dog, Rabbit. Confirm suitability for untested species before use.
Scientific Background
This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2011]
Safety & Handling
This antibody is validated for Western Blot. Recommended dilutions: WB 1:1000-1:2000;Not yet tested in other applications.
Confirmed reactivity: Human, Mouse, Rat, Dog, Rabbit. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
