| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Cell growth inhibiting protein 27;Cell growth-inhibiting gene 27 protein;FGCP;Folate hydrolase;prostate-specific membrane antigen;1;Folate hydrolase 1;Folate hydrolase;Folate hydrolase prostate specific membrane antigen 1;FOLH 1;FOLH;Folh1;FOLH1_HUMAN;Folylpoly gamma glutamate carboxypeptidase;Folylpoly-gamma-glutamate carboxypeptidase;GCP 2;GCP II;GCP2;GCPII;GIG27;Glutamate carboxylase II;Glutamate carboxypeptidase 2;Glutamate carboxypeptidase II;Membrane glutamate carboxypeptidase;mGCP;N acetylated alpha linked acidic dipeptidase 1;N-acetylated-alpha-linked acidic dipeptidase I;NAALAD 1;NAALAD1;NAALAdase;NAALADase I;Prostate specific membrane antigen;Prostate specific membrane antigen variant F;Prostate-specific membrane antigen;PSM;PSMA;Pteroylpoly gamma glutamate carboxypeptidase;Pteroylpoly-gamma-glutamate carboxypeptidase |
| Antigen | |
| Cellular Localization | |
| Clonality | |
| Conjugate | |
| Formulation | |
| Gene ID | |
| Host | |
| Immunogen | Synthesized peptide derived from human Prostate-Specific Membrane Antigen (PSMA) AA range: 100-200 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Product Overview
U-Blot® Prostate Specific Membrane Antigen (PSMA) (ABT-PSMA) Mouse Monoclonal Antibody (WM1447) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against Prostate-Specific Membrane Antigen (PSMA). It has been validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA and reacts with Human, Mouse, Rat.
Validated Applications
| Target | Prostate-Specific Membrane Antigen (PSMA) |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | ABT-PSMA |
| Isotype | IgG1, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat |
| Applications | Immunohistochemistry, Western Blot, Immunofluorescence, ELISA |
| Purification | Protein G |
| Specificity | The antibody can specifically recognize human PSMA protein. In western blotting of LnCap, Hela and MCF7 cell lysates, the antibody can label a specific band corresponding to PSMA only in LnCap cell lysates. |
| Molecular Weight | Calculated: 84 kDa | Observed: 110 kDa |
| UniProt / Swiss-Prot | Q04609 (Human) |
Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Immunogen / Antigen
Synthesized peptide derived from human Prostate-Specific Membrane Antigen (PSMA) AA range: 100-200
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat. Confirm suitability for untested species before use.
Scientific Background
PSMA is a 110 kDa type II transmembrane protein. The gene is located in 11q and is expressed in normal and neoplastic prostate epithelium, as well as in breast, duodenum, colonic mucosa, kidney and tumors of its origin. The expression of PSMA increased after cell carcinogenesis, which was positively correlated with tumor grade and hormone resistance. Combined with PSA can improve the diagnosis of prostate cancer metastasis.
Safety & Handling
This antibody is validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA. Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Confirmed reactivity: Human, Mouse, Rat. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone ABT-PSMA.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
