| Field | Specification |
|---|---|
| Alternative Names | PRDX3;AOP1;Thioredoxin-dependent peroxide reductase;mitochondrial;Antioxidant protein 1;AOP-1;HBC189;Peroxiredoxin III;Prx-III;Peroxiredoxin-3;Protein MER5 homolog |
| Antigen | |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Conjugate | |
| Formulation | |
| Gene ID | |
| Host | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human PRX III. AA range:44-93 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Product Overview
U-Blot® PRX III Rabbit Polyclonal Antibody is a rabbit polyclonal antibody from UcallM Biosciences Inc, raised against PRX III. It has been validated for Western Blot, Immunohistochemistry, Immunoprecipitation, Immunofluorescence, ELISA and reacts with Human, Mouse, Rat.
Validated Applications
| Target | PRX III |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat |
| Applications | Western Blot, Immunohistochemistry, Immunoprecipitation, Immunofluorescence, ELISA |
| Purification | Affinity Purified |
| Specificity | PRX III Polyclonal Antibody detects endogenous levels of PRX III protein. |
| Molecular Weight | Observed: 26 kDa |
| UniProt / Swiss-Prot | P30048 (Human) | P20108 (Mouse) | Q9Z0V6 (Rat) |
Recommended dilutions: WB 1:500-1:2000;IHC:1:50-300;IP 1:50-200;ELISA 1:20000;IF 1:50-200
Immunogen / Antigen
The antiserum was produced against synthesized peptide derived from human PRX III. AA range:44-93
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat. Confirm suitability for untested species before use.
Scientific Background
This gene encodes a mitochondrial protein with antioxidant function. The protein is similar to the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase, and it can rescue bacterial resistance to alkylhydroperoxide in E. coli that lack the C22 subunit. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologs suggest that these genes consist of a family that is responsible for the regulation of cellular proliferation, differentiation and antioxidant functions. This family member can protect cells from oxidative stress, and it can promote cell survival in prostate cancer. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 3, 13 and 22. [provided by RefSeq, Oct 2014]
Safety & Handling
This antibody is validated for Western Blot, Immunohistochemistry, Immunoprecipitation, Immunofluorescence, ELISA. Recommended dilutions: WB 1:500-1:2000;IHC:1:50-300;IP 1:50-200;ELISA 1:20000;IF 1:50-200
Confirmed reactivity: Human, Mouse, Rat. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
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