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Product Overview
U-Blot® RGS6 Rabbit Monoclonal Antibody is a rabbit monoclonal antibody from UcallM Biosciences Inc, raised against RGS6. It has been validated for Western Blot and reacts with Human, Mouse, Rat.
Validated Applications
| Target | RGS6 |
|---|---|
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | PT1124R |
| Isotype | IgG, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat |
| Applications | Western Blot |
| Purification | Protein A |
| Specificity | Endogenous |
| Molecular Weight | Calculated: 52 kDa | Observed: 52 kDa |
| UniProt / Swiss-Prot | P49758 (Human) | Q9Z2H2 (Mouse) | P49801 (Rat) |
Recommended dilutions: WB 1:1000-1:5000
Immunogen / Antigen
Regulator of G-protein signaling 6 (RGS6) (S914)
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat. Confirm suitability for untested species before use.
Scientific Background
This gene encodes a member of the RGS (regulator of G protein signaling) family of proteins, which are defined by the presence of a RGS domain that confers the GTPase-activating activity of these proteins toward certain G alpha subunits. This protein also belongs to a subfamily of RGS proteins characterized by the presence of DEP and GGL domains, the latter a G beta 5-interacting domain. The RGS proteins negatively regulate G protein signaling, and may modulate neuronal, cardiovascular, lymphocytic activities, and cancer risk. Many alternatively spliced transcript variants encoding different isoforms with long or short N-terminal domains, complete or incomplete GGL domains, and distinct C-terminal domains, have been described for this gene, however, the full-length nature of some of these variants is not known.[provided by RefSeq, Mar 2011]
Safety & Handling
This antibody is validated for Western Blot. Recommended dilutions: WB 1:1000-1:5000
Confirmed reactivity: Human, Mouse, Rat. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone PT1124R.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
