| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | Synthesized peptide derived from human Serine/threonine-protein kinase BGLF4 |
| Conjugate | |
| Purification | |
| Concentration | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® Serine/threonine-protein kinase BGLF4 Rabbit Polyclonal Antibody is a rabbit polyclonal antibody from UcallM Biosciences Inc, raised against Serine/threonine-protein kinase BGLF4. It has been validated for ELISA and reacts with the listed species.
Validated Applications
| Target | Serine/threonine-protein kinase BGLF4 |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Reactivity | Human virus |
| Applications | ELISA |
| Purification | Affinity Purified |
| Specificity | This antibody detects endogenous levels of human Serine/threonine-protein kinase BGLF4 |
| UniProt / Swiss-Prot | P13288 (Human) |
Recommended dilutions: ELISA(peptide) 1:5000-20000
Immunogen / Antigen
Synthesized peptide derived from human Serine/threonine-protein kinase BGLF4
Scientific Background
P13288 BGLF4 protein(BGLF4) Human herpesvirus 4 catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Plays many key roles by phosphorylating several proteins including the viral DNA processivity factor BMRF1, EBNA1 or EBNA2. Required for efficient lytic DNA replication and release of nucleocapsids from the nucleus. Contributes to the compaction of host cell chromatin in cells undergoing lytic replication, presumably by phosphorylating the host condensin complex and host TOP2A. Induces disassembly of the nuclear lamina by phosphorylating with host LMNA. Phosphorylates substrates involved in capsid assembly and DNA packaging. Facilitates the switch from latent to lytic DNA replication by down-regulating EBNA1 replication function. Phosphorylates the viral immediate-early protein BZLF1.,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,subcellular location:the protein is present at discrete sites in nuclei, called replication compartments where viral DNA replication occurs.
Safety & Handling
This antibody is validated for ELISA. Recommended dilutions: ELISA(peptide) 1:5000-20000
Confirmed reactivity: the listed species. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
