| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | SGK1 |
| Gene ID | |
| Host | |
| Clone | |
| Clonality | |
| Reactivity | |
| Applications | |
| Immunogen | Synthetic Peptide of SGK1 at AA range of 350-430 |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Concentration | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® SGK1 Mouse Monoclonal Antibody (4D12) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against SGK1. It has been validated for Immunohistochemistry, Immunofluorescence and reacts with Human, Rat, Mouse.
Validated Applications
| Target | SGK1 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 4D12 |
| Conjugate | Unconjugated |
| Reactivity | Human, Rat, Mouse |
| Applications | Immunohistochemistry, Immunofluorescence |
| Purification | Affinity Purified |
| Specificity | SGK1 protein detects endogenous levels of SGK1 |
| Molecular Weight | Observed: 45-60 kDa |
| UniProt / Swiss-Prot | O00141 (Human) | Q9WVC6 (Mouse) | Q06226 (Rat) |
Recommended dilutions: IHC 1:100-200;IF 1:50-200
Immunogen / Antigen
Synthetic Peptide of SGK1 at AA range of 350-430
Reactivity Notes
Confirmed cross-reactivity: Human, Rat, Mouse. Confirm suitability for untested species before use.
Scientific Background
This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009]
Safety & Handling
This antibody is validated for Immunohistochemistry, Immunofluorescence. Recommended dilutions: IHC 1:100-200;IF 1:50-200
Confirmed reactivity: Human, Rat, Mouse. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone 4D12.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
