| Field | Specification |
|---|---|
| Target | |
| Alternative names | 2810449N18Rik;AI043036;Mono ADP ribosyltransferase sirtuin 6;NAD-dependent protein deacetylase sirtuin-6;Regulatory protein SIR2 homolog 6;Regulatory protein SIR2 homolog;SIR2 like 6;SIR2 like protein 6;Sir2 related protein type 6;SIR2-like protein 6;SIR2 |
| Gene ID | |
| Host | |
| Clonality | |
| Reactivity | |
| Applications | |
| Immunogen | Purified recombinant human SIRT6 protein expressed in E.coli. |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® SIRT6 Mouse Monoclonal Antibody is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against SIRT6. It has been validated for Western Blot, Immunofluorescence, Immunoprecipitation and reacts with Human, Mouse, Rat, Monkey.
Validated Applications
| Target | SIRT6 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat, Monkey |
| Applications | Western Blot, Immunofluorescence, Immunoprecipitation |
| Purification | Affinity Purified |
| Specificity | This antibody detects endogenous levels of SIRT6 and does not cross-react with related proteins. |
| Molecular Weight | Observed: 42 kDa |
| UniProt / Swiss-Prot | Q8N6T7 (Human) | P59941 (Mouse) |
Recommended dilutions: WB 1:500;IF/ICC1:100
Immunogen / Antigen
Purified recombinant human SIRT6 protein expressed in E.coli.
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat, Monkey. Confirm suitability for untested species before use.
Scientific Background
This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]
Safety & Handling
This antibody is validated for Western Blot, Immunofluorescence, Immunoprecipitation. Recommended dilutions: WB 1:500;IF/ICC1:100
Confirmed reactivity: Human, Mouse, Rat, Monkey. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
