| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | BIRC5;API4;IAP4;Baculoviral IAP repeat-containing protein 5;Apoptosis inhibitor 4;Apoptosis inhibitor survivin |
| Antigen | |
| Cellular Localization | |
| Clonality | |
| Conjugate | |
| Formulation | |
| Gene ID | |
| Host | |
| Immunogen | Recombinant Protein of Survivin |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Product Overview
U-Blot® Survivin Mouse Monoclonal Antibody (Mix) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against Survivin. It has been validated for Western Blot, Immunohistochemistry, Immunofluorescence and reacts with Human, Rat.
Validated Applications
| Target | Survivin |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Conjugate | Unconjugated |
| Reactivity | Human, Rat |
| Applications | Western Blot, Immunohistochemistry, Immunofluorescence |
| Purification | Affinity Purified |
| Specificity | The antibody detects endogenous Survivin protein. |
| Molecular Weight | Observed: 16 kDa |
| UniProt / Swiss-Prot | O15392 (Human) | O70201 (Mouse) | Q9JHY7 (Rat) |
Recommended dilutions: WB 1:1000-2000;IHC 1:200-500;IF 1:50-200
Immunogen / Antigen
Recombinant Protein of Survivin
Reactivity Notes
Confirmed cross-reactivity: Human, Rat. Confirm suitability for untested species before use.
Scientific Background
This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
Safety & Handling
This antibody is validated for Western Blot, Immunohistochemistry, Immunofluorescence. Recommended dilutions: WB 1:1000-2000;IHC 1:200-500;IF 1:50-200
Confirmed reactivity: Human, Rat. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
