| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Major synaptic vesicle protein p38;MRX96;MRXSYP;Syn p38;Synaptophysin;Syp;SYPH;SYPH_HUMAN;SypI |
| Antigen | |
| Cellular Localization | |
| Clonality | |
| Conjugate | |
| Formulation | |
| Gene ID | |
| Host | |
| Immunogen | Synthesized peptide derived from human Synaptophysin AA range: 200-313 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Product Overview
U-Blot® Synaptophysin (ABT533) Mouse Monoclonal Antibody (WM1449) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against Synaptophysin. It has been validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA and reacts with Human, Mouse, Rat, Bovine.
Validated Applications
| Target | Synaptophysin |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | ABT533 |
| Isotype | IgG1, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat, Bovine |
| Applications | Immunohistochemistry, Western Blot, Immunofluorescence, ELISA |
| Purification | Protein G |
| Specificity | The antibody can specifically recognize human Synaptophysin protein. |
| Molecular Weight | Calculated: 34 kDa | Observed: 38 kDa |
| UniProt / Swiss-Prot | P08247 (Human) | Q62277 (Mouse) | P07825 (Rat) |
Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Immunogen / Antigen
Synthesized peptide derived from human Synaptophysin AA range: 200-313
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat, Bovine. Confirm suitability for untested species before use.
Scientific Background
Synaptophysin is a 38 kDa membrane glycoprotein present in neuroendocrine cells. It is the most abundant synaptic vessel membrane protein, but the function remains unclear. Synaptophysin is mainly expressed in neuroendocrine cells of the human adrenal medulla, carotid body, skin, pituitary, thyroid, lung, pancreas, and gastrointestinal mucosa. The antibodiy is mainly used in the classification of neuroendocrine tumors including neoplasms of epithelial type, nervous system neoplasms with neuronal differentiation and adrenocortical neoplasms.
Safety & Handling
This antibody is validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA. Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Confirmed reactivity: Human, Mouse, Rat, Bovine. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone ABT533.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
