| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | TAF1C;TATA box-binding protein-associated factor RNA polymerase I subunit C ;RNA polymerase I-specific TBP-associated factor 110 kDa;TAFI110;TATA box-binding protein-associated factor 1C;TBP-associated factor 1C;Transcription initiation factor SL1/TIF-IB subunit C |
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Product Overview
U-Blot® TAF1C Rabbit Monoclonal Antibody is a rabbit monoclonal antibody from UcallM Biosciences Inc, raised against TAF1C. It has been validated for Western Blot, Immunoprecipitation and reacts with Human.
Validated Applications
| Target | TAF1C |
|---|---|
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | PT0790R |
| Isotype | IgG, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human |
| Applications | Western Blot, Immunoprecipitation |
| Purification | Protein A |
| Specificity | Endogenous |
| Molecular Weight | Observed: 96 kDa |
| UniProt / Swiss-Prot | Q15572 (Human) | Q6PDZ2 (Mouse) | Q6P773 (Rat) |
Recommended dilutions: WB 1:1000-5000;IP 1:50-100
Immunogen / Antigen
TATA box-binding protein-associated factor RNA polymerase I subunit C;RNA polymerase I-specific TBP-associated factor 110 kDa;TAFI110;TATA box-binding protein-associated factor 1C;TBP-associated factor 1C;Transcription initiation factor SL1/TIF-IB subunit C
Reactivity Notes
Confirmed cross-reactivity: Human. Confirm suitability for untested species before use.
Scientific Background
Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2011]
Safety & Handling
This antibody is validated for Western Blot, Immunoprecipitation. Recommended dilutions: WB 1:1000-5000;IP 1:50-100
Confirmed reactivity: Human. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone PT0790R.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
