U-Blot® Tau Mouse Monoclonal Antibody (10E3)

SKU:BHA21802758
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UcallM Biosciences Inc
UcallM Biosciences Inc
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Overview
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Anti-Tau antibody (Mouse host, monoclonal, Unconjugated). Validated for Western Blot, Immunohistochemistry, Immunofluorescence with reactivity to Human, Rat, Mouse.
Clonality Monoclonal
Host Mouse
Reactivity Human, Rat, Mouse
Conjugate Unconjugated
Clone 10E3
Applications Western Blot, Immunohistochemistry, Immunofluorescence
Options selector
Catalog no. Size
WM1204-50 50 uL
WM1204-100 100 uL
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 50 uL
  • Lead time: options listed in "Availability Content"; other statuses may take longer.
  • Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
  • Shipping: cold-chain shipment (typically with ice packs).
  • Upon receipt: store at recommended temperature as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Target Tau
Antigen
  • MAPT
Alternative names MAPT
Gene ID 4137 (Human)
Host Mouse
Clone 10E3
Clonality
  • Monoclonal
Reactivity
  • Human
  • Rat
  • Mouse
Applications
  • Western Blot
  • Immunohistochemistry
  • Immunofluorescence
Immunogen Synthetic Peptide of Tau
Conjugate
  • Unconjugated
Molecular weight Observed: 50-85 kDa
Purification Affinity Purified
Cellular localization Cytoplasm, cytosol . Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm, cytoskeleton . Cell projection, axon . Cell projection, dendrite . Secreted . Mostly found in the axons of neurons, in the cytosol and in association with plasma membrane components (PubMed:10747907). Can be secreted; the secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion (PubMed:32272059). .
Concentration 1 mg/ml
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage -15°C to -25°C/1 year(Do not lower than -25°C)
Catalog no. (Mfr.) WM1204
Main SKU BHA21802758
Antibody

Product Overview

U-Blot® Tau Mouse Monoclonal Antibody (10E3) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against Tau. It has been validated for Western Blot, Immunohistochemistry, Immunofluorescence and reacts with Human, Rat, Mouse.

Validated Applications

Target Tau
Host Mouse
Clonality Monoclonal
Clone 10E3
Conjugate Unconjugated
Reactivity Human, Rat, Mouse
Applications Western Blot, Immunohistochemistry, Immunofluorescence
Purification Affinity Purified
Specificity Tau protein detects endogenous levels of MAPT
Molecular Weight Observed: 50-85 kDa
UniProt / Swiss-Prot P10636 (Human) | P10637 (Mouse) | P19332 (Rat)

Recommended dilutions: WB 1:1000-2000;IHC 1:100-200;IF 1:50-200

Immunogen / Antigen

Synthetic Peptide of Tau

Reactivity Notes

Confirmed cross-reactivity: Human, Rat, Mouse. Confirm suitability for untested species before use.

Scientific Background

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008]

Safety & Handling

For Research Use Only (RUO). Not for diagnostic or therapeutic use. Store as indicated: -15°C to -25°C/1 year(Do not lower than -25°C)
What applications is this antibody validated for?

This antibody is validated for Western Blot, Immunohistochemistry, Immunofluorescence. Recommended dilutions: WB 1:1000-2000;IHC 1:100-200;IF 1:50-200

What species does it react with?

Confirmed reactivity: Human, Rat, Mouse. Other species should be validated by the user.

Is this antibody conjugated?

Conjugate: Unconjugated.

How should it be stored?

Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)

What is the clone number?

Clone 10E3.

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