| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | TBP;GTF2D1;TF2D;TFIID;TATA-box-binding protein;TATA sequence-binding protein;TATA-binding factor;TATA-box factor;Transcription initiation factor TFIID TBP subunit |
| Gene ID | |
| Host | |
| Clone | |
| Clonality | |
| Reactivity | |
| Applications | |
| Immunogen | Recombinant Protein of TBP/TATA Binding Protein |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Concentration | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® TBP/TATA Binding Protein Mouse Monoclonal Antibody (1F6) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against TBP/TATA Binding Protein. It has been validated for Immunohistochemistry, Immunofluorescence and reacts with Human, Rat, Mouse.
Validated Applications
| Target | TBP/TATA Binding Protein |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 1F6 |
| Conjugate | Unconjugated |
| Reactivity | Human, Rat, Mouse |
| Applications | Immunohistochemistry, Immunofluorescence |
| Purification | Affinity Purified |
| Specificity | TBP/TATA Binding Protein protein detects endogenous levels of TBP/TATA Binding Protein |
| Molecular Weight | Observed: 35-45 kDa |
| UniProt / Swiss-Prot | P20226 (Human) | P29037 (Mouse) |
Recommended dilutions: IHC 1:50-200;IF 1:50-200
Immunogen / Antigen
Recombinant Protein of TBP/TATA Binding Protein
Reactivity Notes
Confirmed cross-reactivity: Human, Rat, Mouse. Confirm suitability for untested species before use.
Scientific Background
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA bin
Safety & Handling
This antibody is validated for Immunohistochemistry, Immunofluorescence. Recommended dilutions: IHC 1:50-200;IF 1:50-200
Confirmed reactivity: Human, Rat, Mouse. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone 1F6.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
