| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Anti TCL1A;Lymphoma/leukemia, T-cell;Oncogene TCL-1;Oncogene TCL1;P14 TCL1;P14 TCL1 protein;Protein p14 TCL1;T cell leukemia 1;T cell lymphoma 1;T cell lymphoma 1A;T-cell leukemia/lymphoma 1A;T-cell leukemia/lymphoma protein 1A;TCL 1 protein;TCL1;TCL1 oncogene;TCL1 PEN;Tcl1a;TCL1A;TCL1A_HUMAN |
| Antigen | |
| Cellular Localization | |
| Clonality | |
| Conjugate | |
| Formulation | |
| Gene ID | |
| Host | |
| Immunogen | Synthesized peptide derived from human TCL1 AA range: 50-114 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Product Overview
U-Blot® TCL1 (ABT378) Mouse Monoclonal Antibody (WM1492) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against TCL1. It has been validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA and reacts with Human.
Validated Applications
| Target | TCL1 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | ABT378 |
| Isotype | IgG2b, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human |
| Applications | Immunohistochemistry, Western Blot, Immunofluorescence, ELISA |
| Purification | Protein G |
| Specificity | The antibody can specifically recognize human TCL1 protein. |
| Molecular Weight | Calculated: 13 kDa | Observed: 13 kDa |
| UniProt / Swiss-Prot | P56279 (Human) |
Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Immunogen / Antigen
Synthesized peptide derived from human TCL1 AA range: 50-114
Reactivity Notes
Confirmed cross-reactivity: Human. Confirm suitability for untested species before use.
Scientific Background
TCL1 belongs to the proto oncogene family. It promotes the nuclear translocation of AKT1 by activating the phosphorylation of AKT1, AKT2 and Akt3, so as to promote cell proliferation and survival and stabilize mitochondrial membrane potential. The encoded protein is involved in embryonic development, T cell carcinogenesis, pre lymphocyte carcinogenesis and B cell carcinogenesis.
Safety & Handling
This antibody is validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA. Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Confirmed reactivity: Human. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone ABT378.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
