| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | ERCC3;XPB;XPBC;TFIIH basal transcription factor complex helicase XPB subunit;Basic transcription factor 2 89 kDa subunit;BTF2 p89;DNA excision repair protein ERCC-3;DNA repair protein complementing XP-B cells;TFIIH basal transcripti |
| Gene ID | |
| Host | |
| Clonality | |
| Reactivity | |
| Applications | |
| Immunogen | Purified recombinant human TFIIH p89 (C-terminus) protein fragments expressed in E.coli. |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® TFIIH p89 Mouse Monoclonal Antibody is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against TFIIH. It has been validated for Western Blot and reacts with Human, Mouse, Rat, Bovine, Dog.
Validated Applications
| Target | TFIIH |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat, Bovine, Dog |
| Applications | Western Blot |
| Purification | Affinity Purified |
| Specificity | TFIIH p89 Monoclonal Antibody detects endogenous levels of TFIIH p89 protein. |
| Molecular Weight | Calculated: 89 kDa |
| UniProt / Swiss-Prot | P19447 (Human) | P49135 (Mouse) | Q4G005 (Rat) |
Recommended dilutions: WB 1:1000-1:2000;Not yet tested in other applications.
Immunogen / Antigen
Purified recombinant human TFIIH p89 (C-terminus) protein fragments expressed in E.coli.
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat, Bovine, Dog. Confirm suitability for untested species before use.
Scientific Background
This gene encodes an ATP-dependent DNA helicase that functions in nucleotide excision repair. The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and, therefore, also functions in class II transcription. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Safety & Handling
This antibody is validated for Western Blot. Recommended dilutions: WB 1:1000-1:2000;Not yet tested in other applications.
Confirmed reactivity: Human, Mouse, Rat, Bovine, Dog. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
