| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Gene ID | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | Synthesized peptide derived from human TGF β Receptor I AA range: 34-100 |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® TGF β Receptor I (ABT-TGFR1) Mouse Monoclonal Antibody is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against TGF β Receptor I. It has been validated for Immunohistochemistry, Immunofluorescence, ELISA and reacts with Human, Mouse, Rat, Bovine.
Validated Applications
| Target | TGF β Receptor I |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | ABT-TGFR1 |
| Isotype | IgG2a, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat, Bovine |
| Applications | Immunohistochemistry, Immunofluorescence, ELISA |
| Purification | Affinity Purified |
| Specificity | This antibody detects endogenous levels of TGF β Receptor I protein. |
| Molecular Weight | Calculated: 55 kDa | Observed: 55 kDa |
| UniProt / Swiss-Prot | P36897 (Human) |
Recommended dilutions: IHC 1:50-200;IF 1:50-200;ELISA 1:500-5000
Immunogen / Antigen
Synthesized peptide derived from human TGF β Receptor I AA range: 34-100
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat, Bovine. Confirm suitability for untested species before use.
Scientific Background
The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Safety & Handling
This antibody is validated for Immunohistochemistry, Immunofluorescence, ELISA. Recommended dilutions: IHC 1:50-200;IF 1:50-200;ELISA 1:500-5000
Confirmed reactivity: Human, Mouse, Rat, Bovine. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone ABT-TGFR1.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
