| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | AV026640;BCH;Benign chorea;BHC;Homeobox protein NK 2 homolog A;Homeobox protein NK-2 homolog A;Homeobox protein Nkx 2.1;Homeobox protein Nkx-2.1;Homeobox protein Nkx2.1;NK 2;NK 2 homolog A;NK2;NK2 homeobox 1;NK2, drosophila, homolog of, A;NK2.1, Mouse, homolog of;Nkx 2 1;NKX 2.1;NKX 2A;NKX2 1;Nkx2-1;NKX2.1;NKX21_HUMAN;NKX2A;T EBP;T/EBP;TEBP;Thyroid nuclear factor 1;Thyroid nuclear factor;Thyroid specific enhancer binding protein;Thyroid transcription factor 1;Tin man;Tinman;TITF 1;TITF1;TTF 1;TTF-1;TTF1 |
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Product Overview
U-Blot® TTF1 Rabbit Monoclonal Antibody is a rabbit monoclonal antibody from UcallM Biosciences Inc, raised against TTF-1. It has been validated for Western Blot, Immunohistochemistry, Immunofluorescence, ELISA and reacts with Human, Mouse, Rat.
Validated Applications
| Target | TTF-1 |
|---|---|
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | PT0661R |
| Isotype | IgG, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat |
| Applications | Western Blot, Immunohistochemistry, Immunofluorescence, ELISA |
| Purification | Protein A |
| Specificity | Endogenous |
| Molecular Weight | Calculated: 40 kDa | Observed: 40 kDa |
| UniProt / Swiss-Prot | P43699 (Human) | P50220 (Mouse) | P23441 (Rat) |
Recommended dilutions: IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000
Immunogen / Antigen
AV026640;BCH;Benign chorea;BHC;Homeobox protein NK 2 homolog A;Homeobox protein NK-2 homolog A;Homeobox protein Nkx 2.1;Homeobox protein Nkx-2.1;Homeobox protein Nkx2.1;NK 2;NK 2 homolog A;NK2;NK2 homeobox 1;NK2, drosophila, homolog of, A;NK2.1, mouse, homolog of;Nkx 2 1;NKX 2.1;NKX 2A;NKX2 1;Nkx2-1;NKX2.1;NKX21_HUMAN;NKX2A;T EBP;T/EBP;TEBP;Thyroid nuclear factor 1;Thyroid nuclear factor;Thyroid specific enhancer binding protein;Thyroid transcription factor 1;Tin man;Tinman;TITF 1;TITF1;TTF 1;TTF-1;TTF1
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat. Confirm suitability for untested species before use.
Scientific Background
This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. [provided by RefSeq, Feb 2014]
Safety & Handling
This antibody is validated for Western Blot, Immunohistochemistry, Immunofluorescence, ELISA. Recommended dilutions: IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000
Confirmed reactivity: Human, Mouse, Rat. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone PT0661R.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
