| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | UPB1;BUP1;Beta-ureidopropionase ;BUP-1;Beta-alanine synthase;N-carbamoyl-beta-alanine amidohydrolase |
| Gene ID | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® UPB1 Rabbit Monoclonal Antibody is a rabbit monoclonal antibody from UcallM Biosciences Inc, raised against UPB1. It has been validated for Western Blot, Immunohistochemistry, Immunoprecipitation and reacts with Human.
Validated Applications
| Target | UPB1 |
|---|---|
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | PT0799R |
| Isotype | IgG, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human |
| Applications | Western Blot, Immunohistochemistry, Immunoprecipitation |
| Purification | Protein A |
| Specificity | Endogenous |
| Molecular Weight | Observed: 42 kDa |
| UniProt / Swiss-Prot | Q9UBR1 (Human) | Q8VC97 (Mouse) | Q03248 (Rat) |
Recommended dilutions: WB 1:1000-5000;IHC 1:100-300;IP 1:50-100
Immunogen / Antigen
Beta-ureidopropionase;BUP-1;Beta-alanine synthase;N-carbamoyl-beta-alanine amidohydrolase
Reactivity Notes
Confirmed cross-reactivity: Human. Confirm suitability for untested species before use.
Scientific Background
This gene encodes a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity. [provided by RefSeq, Jul 2008]
Safety & Handling
This antibody is validated for Western Blot, Immunohistochemistry, Immunoprecipitation. Recommended dilutions: WB 1:1000-5000;IHC 1:100-300;IP 1:50-100
Confirmed reactivity: Human. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone PT0799R.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
