| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | CDH5;Cadherin-5;7B4 antigen;Vascular endothelial cadherin;VE-cadherin;CD144 |
| Antigen | |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Conjugate | |
| Formulation | |
| Gene ID | |
| Host | |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human CDH5. AA range:391-440 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Product Overview
U-Blot® VE-Cadherin Rabbit Polyclonal Antibody (WP15609) is a rabbit polyclonal antibody from UcallM Biosciences Inc, raised against VE-Cadherin. It has been validated for Immunofluorescence, Western Blot, Immunohistochemistry, ELISA and reacts with Human, Mouse, Rat.
Validated Applications
| Target | VE-Cadherin |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat |
| Applications | Immunofluorescence, Western Blot, Immunohistochemistry, ELISA |
| Purification | Affinity Purified |
| Specificity | VE-Cadherin Polyclonal Antibody detects endogenous levels of VE-Cadherin protein. |
| Molecular Weight | Calculated: 86 kDa | Observed: 110-130 kDa |
| UniProt / Swiss-Prot | P33151 (Human) | P55284 (Mouse) |
Recommended dilutions: IF 1:50-200;WB 1:500-2000;ELISA 1:10000-20000;IHC 1:50-300
Immunogen / Antigen
The antiserum was produced against synthesized peptide derived from the Internal region of human CDH5. AA range:391-440
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat. Confirm suitability for untested species before use.
Scientific Background
This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. [provided by RefSeq, Nov 2015]
Safety & Handling
This antibody is validated for Immunofluorescence, Western Blot, Immunohistochemistry, ELISA. Recommended dilutions: IF 1:50-200;WB 1:500-2000;ELISA 1:10000-20000;IHC 1:50-300
Confirmed reactivity: Human, Mouse, Rat. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
