| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | WIT 2;WT 1;AWT1;FWT1;GUD;NPHS4;WAGR;Wilms tumor 1;Wilms Tumor;Wilms tumor protein;Wilms' tumor gene;Wilms' tumor protein;WIT2;WT;WT1;WT1_HUMAN;WT33 |
| Antigen | |
| Cellular Localization | |
| Clonality | |
| Conjugate | |
| Formulation | |
| Gene ID | |
| Host | |
| Immunogen | Synthesized peptide derived from human Wilms' Tumor 1(WT1) AA range: 350-449 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Product Overview
U-Blot® Wilms' Tumor 1(WT1) (ABT-WT1) Mouse Monoclonal Antibody (WM1453) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against Wilms' Tumor 1. It has been validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA and reacts with Human, Mouse, Rat, Pig.
Validated Applications
| Target | Wilms' Tumor 1 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | ABT-WT1 |
| Isotype | IgG2b, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat, Pig |
| Applications | Immunohistochemistry, Western Blot, Immunofluorescence, ELISA |
| Purification | Protein G |
| Specificity | The antibody can specifically recognize human WT1 protein. |
| Molecular Weight | Calculated: 55 kDa | Observed: 55 kDa |
| UniProt / Swiss-Prot | P19544 (Human) |
Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Immunogen / Antigen
Synthesized peptide derived from human Wilms' Tumor 1(WT1) AA range: 350-449
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat, Pig. Confirm suitability for untested species before use.
Scientific Background
WT1, located on chromosome 11p13, is a tumor suppressor gene, which mainly plays a role in the development of genitourinary organs. It was positive in ovarian serous carcinoma, peritoneal serous carcinoma, ovarian metastatic carcinoma, 50% of ovarian endometrial carcinoma, posterior renal adenoma, most malignant mesothelioma and sex cord stromal tumor.
Safety & Handling
This antibody is validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA. Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Confirmed reactivity: Human, Mouse, Rat, Pig. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone ABT-WT1.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
