| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | XRCC4;DNA repair protein XRCC4;X-ray repair cross-complementing protein 4 |
| Gene ID | |
| Host | |
| Clone | |
| Clonality | |
| Reactivity | |
| Applications | |
| Immunogen | Synthetic Peptide of XRCC4 |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® XRCC4 Mouse Monoclonal Antibody (5C10) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against XRCC4. It has been validated for Western Blot, Immunohistochemistry, Immunofluorescence, Immunoprecipitation and reacts with Human.
Validated Applications
| Target | XRCC4 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 5C10 |
| Conjugate | Unconjugated |
| Reactivity | Human |
| Applications | Western Blot, Immunohistochemistry, Immunofluorescence, Immunoprecipitation |
| Purification | Affinity Purified |
| Specificity | The antibody detects endogenous XRCC4 proteins. |
| Molecular Weight | Observed: 38 kDa |
| UniProt / Swiss-Prot | Q13426 (Human) | Q924T3 (Mouse) |
Recommended dilutions: WB 1:2000;IP 1:200;IF 1:200;IHC 1:50-300
Immunogen / Antigen
Synthetic Peptide of XRCC4
Reactivity Notes
Confirmed cross-reactivity: Human. Confirm suitability for untested species before use.
Scientific Background
The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternative splicing generates several transcript variants. [provided by RefSeq, Dec 2015]
Safety & Handling
This antibody is validated for Western Blot, Immunohistochemistry, Immunofluorescence, Immunoprecipitation. Recommended dilutions: WB 1:2000;IP 1:200;IF 1:200;IHC 1:50-300
Confirmed reactivity: Human. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone 5C10.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
