UCHL3 Antibody

SKU:BHA17136339
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NSJ Bioreagents
NSJ Bioreagents
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Overview
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Anti-UCHL3 antibody from Rabbit, recombinant rabbit monoclonal, clone 26U65, Rabbit IgG. Recommended for workflows such as Western blot (WB), Immunofluorescence (IF). Reactivity: Human, Mouse, Rat.
Target UCHL3
Clone Number 26U65
Host Rabbit
Reactivity Human, Mouse, Rat
Application WB, IF
Options selector
Catalog no. Formulation Size
RQ8920 Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Formulation: Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA; Size: 100 ul
  • Lead time: typically ships in ~2-3 business days; timing may vary by selected option.
  • Storage: Store the UCHL3 antibody at -20oC.
  • Shipping: cold-chain shipment (typically with ice packs).
  • Upon receipt: store at the recommended temperature as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Mfr No RQ8920
Clonality
  • Recombinant Rabbit Monoclonal
Host Rabbit
Immunogen A synthetic peptide specific to human UCHL3 was used as the immunogen for the UCHL3 antibody.
Isotype
  • Rabbit IgG
Product Type
  • Antibodies
  • Primary Antibodies
Purity Affinity purified
Reactivity
  • Human
  • Mouse
  • Rat
Storage Store the UCHL3 antibody at -20oC.
Target UCHL3
UniProt # P15374

Overview

UCHL3 Antibody is a anti-UCHL3 Rabbit antibody Recombinant Rabbit Monoclonal clone 26U65 supplied in Purified format. Recommended for workflows such as Western blot (WB), Immunofluorescence (IF) with listed reactivity in Human, Mouse, Rat. Reported localization: Nucleus, Cytoplasm, Golgi.

Key elements and design rationale

  • Target: UCHL3
  • Antibody details: Rabbit, Recombinant Rabbit Monoclonal, clone 26U65, isotype Rabbit IgG
  • Format: Purified
  • Applications (as listed): WB, IF

Biological background

UCHL3 (Ubiquitin carboxyl-terminal hydrolase isozyme L3) is a deubiquitinating enzyme that belongs to the ubiquitin C-terminal hydrolase family. It functions by processing ubiquitin precursors and recycling ubiquitin from ubiquitinated proteins, thereby maintaining cellular ubiquitin homeostasis. Researchers often use a UCHL3 antibody to explore its role in protein turnover and cellular quality control.

UCHL3 is widely expressed across tissues and has been linked to key biological processes including DNA repair, cell cycle regulation, and stress responses. Dysregulation of UCHL3 has been associated with cancer, neurodegeneration, and impaired protein degradation pathways. Employing a UCHL3 antibody provides insights into its diverse cellular functions and disease associations.

Research relevance and current trends

  • Connecting protein-level changes to phenotype using orthogonal readouts (genetic perturbation, transcriptomics, imaging).
  • Considering isoforms and post-translational regulation when interpreting protein-level changes.
  • Comparing results across species and model systems with matched controls.

Common research applications

  • Western blotting: compare relative abundance and activation-state changes across conditions.
  • Immunofluorescence: visualize subcellular distribution and cell-to-cell heterogeneity.

Interpret changes in signal alongside appropriate controls and, when relevant, in parallel with total-protein or pathway readouts.

Notes for experimental interpretation

  • Signal can reflect expression level, isoform composition, and post-translational state; interpret results in the context of your model system and stimuli.
  • Species differences and sample matrices can influence epitope recognition; prioritize matched controls and orthogonal confirmation when feasible.

Antibody notes: Monoclonal antibodies provide a defined epitope recognition profile that can support consistent comparisons across experiments.

Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.

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Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

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